ABO
Rh
Other Blood Groups
Lewis
Testing Methods
Blood Donors
200
This sugar defines the B antigen
D-galactose
200
The most common Rh phenotype that would be capable of forming anti-G
dce/dce
r/r
200
Patients of African descent who are double Duffy negative are unlikely to form which Duffy antibody?
Anti-Fyb – Most patients of African descent have GATA box mutations in promoter region and make Fyb in other tissues but not on RBCs and therefore don’t typically form Anti-Fyb
200
Which precursor chain is present on red blood cells (Type 1 or 2)?
Type 2
200
LISS and PEG are potentiating reagents that enhance reactions by doing what?
LISS decreases the zeta potential between RBCs and PEG extrudes water molecules between cells
200
Deferral for Plavix (clopidogrel)
14 days
400
What sugar is this on the H antigen?
Fuctose
400
The most common Rh positive phenotype (Weiner terminology) in African Americans is?
R0
400
Antibodies to this blood group system are notorious for decreasing to undetectable levels and also for showing dosage?
Kidd
400
The Se gene encodes this enzyme?
FUT2
400
Who is eligible for an electronic crossmatch?
Patients with no antibodies
400
Travel to a malaria endemic region has how long of deferral?
3 Months
600
This blood group has the least quantity of exposed H antigen
Group A1B
600
Are Rh antigens destroyed or enhanced by enzymes?
Enhanced: Lewis is a PeeIing Rhotten Kidd
600
Anti-P biphasic hemolysin antibodies seen in Paroxysmal Cold Hemoglobinuria (PCH) can be identified using this test?
Donath-Landsteiner
600
FUT3 is encoded by this gene?
Le
600
A patient with a warm autoantibody who has been recently transfused should have this test to rule out possible underlying allogeneic antibodies
Allogeneic or Differential Adsorption
600
Potential donors who have stigmata of IV drug use are deferred for how long ?
Indefinite
800
The genotype hh, Sese produces this phenotype
Para-Bombay
800
This Rh genotype is called a “full house” because individuals have all the Rh antigens (D, C, E, c, e)
R1/R2
DCe/DcE
Also R2/r’ and RZ/r and R0/ry
800
Antibodies which demonstrate weak reactivity against many cells in an antibody panel and continue to react at high dilutions are called?
High Titer Low Avidity (HTLA)
Examples include: Chido/Rogers (Ch/Rg), Sda, Cartwright, John Milton Hagen (JMH)
800
People who express Le(a) but not Le(b) in secretions and on red blood cells must lack this gene?
Se
800
Who is eligible for a Type and Screen 30?
A patient going for outpatient surgery who has not been transfused or pregnant in the past 3 months.
800
Name something that leads to a 12 month deferral
Hep B immune globulin
Any unlisted vaccine
Incarceration > 72 hours
1000
How can 2 parents who type as O have a type A baby?
One is Bombay phenotype and genetically type A.
1000
f is the combination of ce.
What is the combination of Ce called?
Rh7
1000
If you lack the U antigen, what other major structure on your RBCs do you lack?
Glycophorin B
1000
A person has the genotype Hh, Sese, and Lele. What antigens will his/her red cells demonstrate?
H, Le(b)
1000
A patient with a positive DAT showing reactivity at IgG phase suspected to be due to drug effect would show the following result on elution?
Negative with all tested panel cells because the antibody is directed against drug coated RBCs. A warm autoantibody that is not drug-related generally shows all positive cells in a panel on elution
1000
Deferral for living in a malaria endemic region for >5 years
3 years