Definition
Physiology
Practical steps
Pharmacology
100

The primary component in blood responsible for forming the initial platelet plug at the site of vascular injury

Platelets

200

An intervention used during a massive transfusion to prevent coagulopathy and hypothermia by ensuring blood products are at body temperature.

Warming blood and intravenous fluids

200

This medication, which is an anti-fibrinolytic agent, is recommended early in the management of traumatic haemorrhage to help stabilise clots.

Tranexamic Acid (TXA)

300

When assessing the 'C' (Circulation) in the ABCDE approach, the presence of these two pulses suggests a systolic blood pressure of at least 60 mmHg and 80 mmHg, respectively.

Carotid and femoral

300

This intraosseous (IO) access site is considered the most reliable and safest for immediate fluid and blood administration in adults.

Proximal humerus

400

This is the earliest physiological indicator of hypovolaemic shock in an adult, which may remain normal even after a 15% blood loss.

Tachycardia (heart rate)

500

50% loss of blood volume in 3 hours or 150ml/min

Major haemorrhage

500

Poor pallor, reduced urine production.

Vasoconstriction

500

This blood component is typically given to restore the clotting factors, especially after a significant loss of whole blood.

Fresh Frozen Plasma (FFP)

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