Topic 12
This type of transport can move between almost all intracellular compartments EXCEPT the mitochondria, plastids, cytosol, and nucleus.
What is Vesicular Transport?
This molecular switch will increase the order in the cell.
What is Ran GTPase?
These small membrane- bound sacs carry proteins and lipids between organelles, including the ER and Golgi
What are transport vesicles?
Small vesicles derived from the endoplasmic reticulum fragments.
What are Microsomes?
This protein binds ribosomes that contain growing sequences of peptides to a receptor on the ER membrane that then results in translocation and folding of the peptide.
What is SRP?
Formic acid, Formaldehyde, and Alcohol can be oxidized by this enzyme.
What is Catalase?
This organelle, often described as the cell’s “post office”, sorts and modifies proteins before sending them to their final destinations
What is the Golgi apparatus?
This organelle is responsible for the modification and transport of proteins.
What is Endoplasmic Reticulum (ER)?
This ER membrane participates in post-translational translocation in eukaryotes, bacteria, and archaea.
What is the Sec61 complex?
This translocator can transport fully loaded and oligomeric proteins across the membrane.
What is the peroxisomal translocator?
Coated vesicles that travel from the plasma membrane inward often use this protein coat
What is clarthrin?
This amino acid sequence works as a zip code to help determine the protein sorting destination.
What is a Signal Sequence?
This is an ER chaperone protein that assists in protein folding and managing misfolded or partially folded proteins.
What is BiP?
These types of proteins will use their internal signal sequences to enter the intermembrane space via TOM.
What are multipass transmembrane proteins?
These small GTP-binding proteins act as molecular switches to regulate vesicle budding, movement, and tethering.
What are Rab GTPases?
This glycolipid modifies many surface proteins to help them attach to the cell membrane.
What is a Glycosylphosphatidylinositol (GPI) anchor?
This type of pathway/response results in the reduction of proteins entering the ER and an activation of genes that lead to protein folding capacity and degradation.
What is Unfolded Protein Response?
These two drugs will inhibit calcineurin dephosphorylation of NF-AT, and therefore, will inhibit T cell activation.
What is Cyclosporin A and FK506?
Fusion of a vesicle with its target membrane requires this family of proteins
What are SNARE proteins?
This protein is required to import many of the proteins into the mitochondria.
What is Cytosolic HSP70?