Topic 12
Proteins that are recruited by scaffold molecules and can be locally concentrated within the biomolecular condensate.
What are client molecules?
This is the major membrane phospholipid of the ER
What is Phosphatidylcholine?
Three heavy and three light chains come together to give clathrin this unique structure
What is Triskelion?
This class of enzymes catalyze the attachment of specific amino acids to their corresponding tRNA molecules.
What are aminoacyl-tRNA synthetases?
This type of biomolecular condensate’s function is the localization and inheritance of mRNAs and organelles
What is Balbiani body?
This forms from sphingosine and travels to the Golgi where it serves as a precursor for glycosphingolipids and sphingomyelin.
What is Ceramide?
Not only do these molecules add specificity to vesicle formation, but the location of phosphorylation changes their name
What are PIPs?
This term describes proteins that bind to enhancer regions and play a role in regulating eukaryotic gene expression.
What are transcription factors?
This complex helps to fold proteins properly in the outer membrane without the help of TOM.
What is the SAM complex?
If n-terminal signal is present as translation begins, this binds to bring ribosomal mRNA and growing peptide to ER membrane.
What is SRP?
Transport out of the golgi stacks stays nice and organized with the help of these coiled-coil proteins
What are Golgins?
Transmembrane receptors can be recycled thanks to the formation of these special vesicles
What are Retromers?
This allows for passage of proteins and other macromolecules in and out of the nucleus.
What are nuclear pores?
All proteins that enter the intermembrane space of the mitochondria must pass through this translocator
What is the TOM Complex?
When the lysosome is the destination, this signaling protein ensures cargo gets there on time
What is mannose-6-phosphate?
Proteins containing cysteine motifs can be oxidized to disulfide bonds with this helpful enzyme
What is Mia40?
In mitosis, this breaks down along with the lamina and nuclear pores.
What is the nuclear envelope?
This GTPase deactivating protein is closely associated with chromatin
What is Ran GEF?
With clathrin or without, a thirsty cell can take a drink with this thirst quenching process
What is Pinocytosis?
This enzyme can be found around the neck of a budding vesicle and uses GTPase activity to constrict the plasma membrane to cause separation of the developing vesicle and the membrane.
What is dynamin?