This is the most appropriate first diagnostic step in a patient with a first time unprovoked seizure
Head CT
This is the treatment of choice for patients with bleeding and hypofibrinogenemia in the setting of DIC
Cryoprecipitate
This is the most appropriate medication to treat dermatitis herpetiformis
Dapsone
A patient with a family history of RA presents for evaluation. She consumes alcohol, smokes tobacco, eats junk food, and does not exercise. This is the most appropriate preventive measure to take for this patient to prevent RA.
Smoking cessation
A 48 year-old female presents for a yearly physical examination. She has a 2/6 systolic murmur at the left sternal border without radiation. She denies symptoms. This is the most appropriate next step.
Routine follow up
A patient presents with morning headaches, difficulty with focus, and short term memory issues. He has missed several meetings at work and falls asleep in others. He scores a 25/30 on MMSE. This is the best initial diagnostic test.
Polysomnography
This is the most appropriate treatment for cold-agglutinin disease (hemolysis).
Rituximab (and cold avoidance)
This is the initial screening test that should be pursued in a patient with acanthosis nigricans.
Fasting blood glucose
This is the treatment of choice for scleroderma renal crisis
Captopril
A patient undergoes a right hemicolectomy for colon cancer. This is when her next colonoscopy should be performed.
1 year after diagnosis
A female patient with juvenile myoclonal epilepsy (on Valproate) presents for pre-conception counseling. Valproate is tapered off. These are the two medications (you just have to give one) that are recommended for women with childbearing potential.
Levetiracetam and Lamotrigine
This is the most appropriate initial treatment for patients with CML
Imatinib (Tyrosine kinase inhibitors)
A patient with ulcerative colitis presents with an ulcer on her anterior shin. It began as a red papule 2 weeks ago and then became enlarged and ulcerated. This is the most likely diagnosis.
Pyoderma gangenosum
In a patient with fibromyalgia currently on duloxetine and an exercise program, this is the next medication of choice to add to her regimen if symptoms are not adequately controlled
Pregabalin
Relief of pain with elevation of the testis is most likely indicative of this diagnosis
Epididymitis (Prehn sign)
This is the treatment of choice for fatigue in a patient with multiple sclerosis who has had a negative laboratory workup, takes Vitamin D, and a negative depression screen.
Modafinil
This is the pre-operative hemoglobin goal for a patient with sickle cell anemia
10g/dL
This is the recommended first line treatment for comedonal acne.
Topical Retinoids
This is the treatment of choice for patients with severe tophaceous gout that have failed standard medical therapies.
Pegloticase (a porcine derived uricase)
A patient is brought to the ICU who had a cardiac arrest after being found in a frozen lake. CPR has been ongoing for 25 minutes, patient's temperature is 82.4 degrees F. This is the most appropriate next step in management.
Continue CPR with active core rewarming
This is the most appropriate initial treatment of intracranial hypotension
Epidural blood patch
This is the most appropriate next step in the evaluation of recurrent colon cancer.
RAS mutation status of primary tumor
This is the treatment of choice for actinic purpura
None, reassurance
An 18 year-old M with a PMH of Kawasaki disease when he was 5 presents for a pre-sports evaluation. This is the complication of the disease most important to rule out to determine his eligibility for sports.
Coronary artery aneurysm
A 24 year-old F is evaluated for 8 months of chronic fatigue, unrefreshing sleep, short term memory loss, and postexertional malaise. She also has lightheadedness and dizziness with upright posture. Labs, depression, and anxiety scores are normal. This is the most likely diagnosis.
Systemic exertion intolerance disease