Signature Tenofovir Resistance Mutation
K65R
This intraerythrocytic pathogen
Babesia spp.
(Maltese cross)
Name 2 causes of pre-formed toxin causing GI symptoms
Staph aureus
Bacillus cereus
Clostridium perfringens
Cause of recurrent Neisseria infections
Terminal complement deficiency (C5-C9)
Precautions for VRE
Standard
Name two bacteria intrinsically resistant to Vancomycin
Lactobacillus
Leuconostoc
Erysipelothrix
Pediococcus
Pathogen responsible for causing this liver abscess:
Klebsiella pneumoniae
(string sign)
GI symptoms wtihin 24h of eating shellfish followed by temporary memory loss resolving within hours to days
Amnesic Shellfish Poisoning
Cause of recurrent sinopulomary infections, enteric infections diagnosed by impaired response to new or recall immunization
CVID
(common variable immunodeficiency)
Name 3 diseases requiring airborne isolation
Smallpox, Measles, TB, SARS, Varicella, Mpox, COVID-19
Two ganciclovir resistance genes in CMV
UL97 & UL54
Cause of these lesions in a septic, cirrhotic patient
Vibrio vulnificus
Rash, diarrhea, flushing,& burning lips hours after eating reef fish
Scrombroid
(histamine fish poisoning)
Recurrent cutaneous and sinopulmonary infections, partial albinism, peripheral neuropathy diagnosed by giant blue granules in neutrophils
Chediak-Higashi Syndrome
The single most effective intervention in preventing health-care associated infection
Hand Hygiene
Echinocandin resistance is primarily mediated my mutations in this drug target gene
FKS1
Biopsy of ulceration shows AFB:
Mycobacterium ulcerans
(Buruli ulcer)
Diarrhea, hemolytic anemia, & thrombocytopenia following infection with this organism
STEC
(Shiga-Toxin producing E. coli)
Immunologic cause of invasive Aspergillosis or Nocardia in a young, otherwise normal host
Chronic Granulomatous Disease
Number of air exchanges needed for an effective negative pressure room
12 exchanges/hour
Besides A. terreus, name two fungi resistant to Amphotericin
Scedosporium spp
Candida lusitaniae
Chromoblastomycosis
Some Fusarium spp
Lactophenol cotton blue stain of blood showing “daisy-shaped” sporangia:
Prototheca wickerhamii
(algae)
Numbness of lips, burning of extremities, vomiting, & temperature reversal 30 minutes after eating coral reef fish; may progress to respiratory failure
Ciguatera
(due to algae toxin)
Recurrent Staph aureus or GAS skin infections,invasive Aspergillosis, hypereosinophilia, eczema & delayed dental deciduation; diagnosed by mutations in STAT3
Hyper IgE Syndrome
(Job’s)
The first step in an outbreak investigation
Establishing the existence of an epidemic