H.M.
Learning and Memory
Chapter 4
Chapter 5
The Developing Brain
100

What was left of H.M.'s memory after his surgery?

Left with amnesia that only provided him with memories of past and facts about his family and self, but was left unable to form NEW memories

100

What type of memory is in use when you run back to your locker to retrieve you phone and jot down a phone number you friend just gave you?

working memory

100

What is synaptic plasticity?

The ability for the synapses to remodel themselves

100
Damage to what area in the brain would result in face blindness?

Fusiform face area (FFA)

100

Which layer during development signals for secretion of the sonic hedgehog signaling molecule?

mesoderm

200
Did H.M. lose his working memory?

no

200

What type of memory would one of being with you family on a summer vacation in 2018 be?

Episodic memories

200
What is the function of the amygdala in regard to memory?

Integrates emotion into memories, especially episodic memories

200

If a patient came in, presenting with the ability to understand words, but the inability to produce coherent words, what might they have?

Broca's aphasia (nonfluent)

200

What is the purpose of a growth cone?

located at the tip of the axon explores the enviornment and seeks out destination during growth of axon

300

What operation did H.M. undergo that left him unable to form new memories?

H.M. had his medial temporal lobes removed along with most of his hippocampus

300

Grid cells are involved in what type of emory and what are their function?

Grid cells are involved in spatial memory, and allow one to perceive exactly where they are in a place.

300
Which part of the brain encodes punishment by inhibiting dopamine release in the brain?

the lateral habenula

300

Damage to the left temporal lobe might result in what?

Wernicke's aphasia (fluent)

300

During synapse formation, what is the purpose of the astrocytes?

they contact neurons and provide support and scaffolding to neurons. 

400

why was H.M.'s non-declaritive memory still intact?

His PFC, cerebellum, basal ganglia were all intact, which are all involved in this type of memory

400

What part of the brain is involved in working memory?

The PFC (prefrontal cortex) is most active during this type of memory

400

Which part of the PFC allows for one to have self regulation and dicipline in decision making?

The lateral PFC

400

what area of the brain is this?

brocas area

400

why do alcohol, cocaine, and other unsafe suba=stances affect the neurological state of the baby?

they disrupt migration, leading to disability or epilepsy

500

If H.M. had instead had parts of his PFC Removed, what types of memory might have been affected?

Working, nondeclaritive, semantic

500

What part of the brain aids the hippocampus in determining the "what" of episodic memories?

The parahippocampal region

500
What is the function of the periaqueductal gray?

It is involved in pain perception and stress response and contains receptors such as those for morphine and oxycodone for reducing pain

500

Damage to FOXP2 gene results in what?

difficulty moving jaw and mouth

500

90% of migration is controlled by what?

the radial glia

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