Objective
What is the population?
Who are adults in high income countries
What are Randomized Control Trials?
How was bias reviewed?
What is duplicate assessment and third author to settle disagreements?
What is the issue with the funnel plot depicting energy data?
What is less than ten study minimum requirement?
What is the intervention?
What 3 databases were searched?
What are PubMed, Ovid Medline and CINAHL?
What tool was utilized to assess bias?
What is Cochrane's tool for assessing bias?
What is the appropriate method to use to analyze combined data when it is heterogeneous?
What is random effects meta-analysis?
What is the control?
What statistic was not mentioned when describing the study selection process?
What is a Kappa statistic?
What was the overall conclusion about the scientific quality of the studies included?
What is low quality due to high bias risk?
How precise were the energy results?
What is not very precise, wide CI; 78/2000=4; 440/2000=22%, therefore between 4-22% of daily calories
What is the outcome?
What is weight change and energy intake?
What potential issue could arise from limiting search to studies in English?
What is Publication Bias?
When evaluating the forest plot for body weight, are results congruent?
Yes, because confidence intervals mostly overlap.
Why were both results considered significant?
What is both resulted in a value with a CI that did not cross the line of significance (0 for continuous data)?
The review protocol being registered with PROSPERO in Feb 2017 indicates what type of design?
What is a priori design?
What was a strength of the search process?
What is reviewing clinical trials that were registered but unpublished/ongoing?
What amount of heterogeneity was identified by the statistical heterogeneity test (I2) for body weight?
What is moderate heterogeneity, 43%?
Is either result clinically significant?
Debate it.