CCIR
What is our protocol CCIR number?
What is.. CCIR 1356
How many sites are involved in this project?
What is.. 11
What does GCP stand for?
What is.. Good Clinical Practice.
What floor is the facility located on?
What is.. the fifth floor
Who is the PI/ Sponsor for the HEAD study?
Who is... Brian Gordon and the University of Pittsburgh
What radiopharmaceuticals does our project utilize? List all possible names.
What is..
Amyloid - Pittsburgh Compound B (PIB)
Tau - Tauvid flortiucipir AV 1451
MK6240
What does NCRAD stand for and where is it located?
What is.. the National Centralized Repository for Alzheimer's Disease and Related Dementias located in Indianapolis, IN.
What is the LAR and the order of priority?
What is.. legally authorized representative.
1. Spouse
2. Adult child
3. Parent
4. Brother or sister
5. Relative by blood or marriage
What cognitive testing is completed in this facility (partially or fully)?
What is.. UDS3, neuro-psych battery, CDR (clinical dementia rating), MMSE (mini mental status exam).
Who is the Authorized User for the HEAD study?
Dr. Cyrus Raji
What is the radiopharmaceutical half life for the tracers?
What is..
Pittsburgh Compound B - 20 min (2 hrs)
AV 1451 - 2 hrs (12 hrs)
MK6240 - 2 hrs (12 hrs)
What is the order of the tubes as they are drawn and what do the colors mean?
What is.. PAXgene, Serum, 10 mL Purple Top EDTA, 6 mL Purple Top EDTA
1. RNA analysis
2. Serum
3. Plasma/ buffy coat
4. Whole blood
Who is... the authorized user....
1. Cyrus Raji
2. Tammie Benzinger
3. Manu Goyal
4. Matt Brier
What are the parameters for centrifuging samples including tube type?
What is.. 4 degrees Celsius, 2000g for 10 min
*as long as samples look good
5 10mL purple top EDTA tubes and serum tube
Who is... Jamie Vaugh
What does CCIR stand for and located on what floor of Barnes-Jewish?
What is.. the Center for Clinical Imaging Research is located on the 10th floor of BJH.
How many participants are approved to be enrolled under this protocol?
What is.. 150 participants.
Where are protocol deviations reported(3)?
Where are samples stored prior to shipment to NCRAD?
Where is... the CORE lab, on the 6th floor of Wohl.
Who is the main study coordinator at University of Pittsburgh?
Who is... Firoza Lussier
Who can give the injections of any radiopharmaceuticals?
Who is.. Linda Becker, Nick Dunn, Laura Fohne, Nelly Miyazaki, and Shirin Hatami.
What information is uploaded into LONI?
What is.. deidentified CSV files and protocol specific images.
What is the range of days to follow up with participants once they've received a tracer?
what is... 5-10 days
How many pounds are packaged in the shipping container (protocol specific and reality)?
Who releases PET imaging dedicated slots (3)?
Who is.... Jennifer Morgan (cyclotron), Linda Becker (CCIR), Kelley Jackson (Benzinger group)