NAS Basics
Treatment Options
Buprenorphine
100

Diagnostic criteria for NAS

What are maternal history and baby's symptoms?

100

First line treatment option for NAS according to CHOC Care Guidelines

What is morphine?

100

A reason why buprenorphine is not used routinely 

What is lack of long-term data, high alcohol content of sublingual solution and no true efficacy data?
200

Substances that can cause NAS

What are medications or illicit drugs? (opioids, stimulants, antidepressants and sedatives)

200

Adjunct treatment options for NAS, often used when exposure was to more than one substance 

What are phenobarbital and clonidine?

200

The two areas where buprenorphine has demonstrated superiority over morphine for NAS

What are decreased length of stay and shortened treatment duration?

300

The three areas of disturbance assessed by Finnegan scoring

What is the CNS, Metabolic/Vasomotor/Respiratory systems and the Gastrointestinal tract?

300

Finnegan scores prompting pharmacologic treatment of NAS

What is the 24 Rule? (2 scores >/=12 or 3 scores >/=8)

300

Proposed half-life of buprenorphine in term neonates

What is 11 hours?

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