MRI Physics & Sequences
MRI: The Basics book
The Brain

MRI & MRS History
Digging Up the Past
100

This parameter primarily affects image contrast in spin echo sequences but not in gradient echo sequences.

What is T2 Relaxation Time?

100

Which of the following metabolites is typically absent in a normal, healthy brain on MR spectroscopy: NAA, lactate, choline, creatine, or myo-inositol?

What is Lactate?

100

This is the average weight of the adult human brain.

What is 3 pounds?



100

This discovery in 1946 by Felix Bloch and Edward Purcell laid the foundation for MRI and earned them the Nobel Prize in Physics in 1952

What is Nuclear Magnetic Resonance (NMR)?

100

B1+ inhomogeneity correction of volumetric brain NOEMTR via high permittivity dielectric padding at 7T 

What is 2023?

200

This physics law is utilized in signal detection when magnetization precesses at a certain frequency in order to receive signal. 


What is Faraday’s Law of Induction? 

200

Increasing TR leads to an increase in...

What is either scan time, SNR, T2W, coverage?

200

This part of the brainstem controls basic functions like breathing and heart rate.  

What is medulla oblongata?

200

This man produced the first human MRI image in the late 1970s and received the 2003 Nobel Prize in Physiology or Medicine for his work

Who is Paul Lauterbur

200

T1ρ relaxation mapping in human osteoarthritis (OA) cartilage: Comparison of T1ρ with T2

What is 2006?

300

In parallel imaging, this reconstruction method uses coil sensitivity profiles to reconstruct under-sampled data.

What is SENSE (Sensitivity Encoding)?

300

The SAR at 3T is approximately this many times higher than at at 1.5T.

What is four times?

300

Glutamate is synthesized from this TCA cycle intermediate.

What is α-ketoglutarate?

300

This scientist is credited with developing in vivo magnetic resonance spectroscopy techniques in the 1980s, particularly for studying brain metabolism.

Who is Richard S. Algers?

300

This is the title of Anshuman's honors undergrad thesis. 

What is High Resolution Magic Angle Spinning and Nuclear Magnetic Resonance Relaxometry Investigations of Tendon?

400

This effect refers to the reduction in T2* decay due to microscopic field inhomogeneities at the cellular level.

What is spin dephasing from susceptibility effects?

400

The following is a drawback of inversion recovery sequences.

What is decreased SNR? 

400

This structure regulates homeostasis and controls the pituitary gland.


What is the hypothalamus?

400

The first MRI contrast agent, based on this paramagnetic element, was introduced in the 1980s to improve lesion detection.

What is gadolinium

400

This is the title of Neil's dissertation.

What is Nonuniform and Non-Cartesian Sampling in Multidimensional Magnetic Resonance Spectroscopic Imaging?

500

This rapid imaging technique collects multiple echoes after a single RF pulse and uses different phase-encoding gradients for each, making it useful for fast T2-weighted imaging but sensitive to blurring and motion.

What is fast spin echo (FSE) or turbo spin echo (TSE)?

500

You want to scan a claustrophobic patient more quickly, so you increase the echo train length; however, the scan time surprisingly doubles over what you would expect. What should you do next?

What is Increase the TR?

500

Diffusion Tensor Imaging (DTI) quantifies anisotropic diffusion in tissues by modeling water movement using this mathematical structure.

What is a tensor?

500

This technique, first demonstrated in humans in 1992 by Seiji Ogawa, uses changes in deoxyhemoglobin levels to infer brain activity.

What is BOLD fMRI (blood oxygen level dependent functional MRI)?

500

"In vivo microstructural white matter changes in early spinocerebellar ataxia 2" is the title of this lab member's first published paper

Who is Sunil?

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