Etiology
Pathophysiology
Clinical Manifestations
Evaluation & Treatment
100

What are chemicals that are known to cause cancer referred to as?

What are carcinogens?

100

What kind of cancer found most commonly in individuals assigned female at birth originates in epithelial tissue lining breast ducts and lobules?

What is breast cancer?

100

What general cancer symptom is characterized by an extreme lack of energy?

What is excessive fatigue?

100

What evaluation technique involves excision of tumor tissue for histological examination?

What is biopsy?

200

What factors are most commonly associated with cancer development?

What is genetic mutation, radiation exposure, chemical/carcinogen exposure, UV, particular viral pathogens?

200

What type of tumor is made of cancerous cells that can spread to other tissues beyond the site where the tumor first originated?

What is a malignant tumor?
200

What is a common general symptom of cancer that involves a persistent lack of appetite?

What is anorexia?

200

In cancer staging, stage 4, characterized by distant spread of malignancy, is also referred to as what?

What is metastatic cancer?

300

What environmental/chemical carcinogen is most commonly attributed to the development of lung cancer, specifically small-cell lung cancer? 

What is cigarette smoking?

300

What is the second stage of carcinogenesis characterized by the proliferation and hyperplasia of preneoplastic cells?

What is promotion?

300

What are the common clinical manifestations related to lung cancer?

What is persistent coughing, wheezing, dyspnea, and bloody sputum?

300

What specific cancer therapy method involves enhancing the body's own immune system to fight cancer?

What is immunotherapy?

400

What is the high risk virus strain attributed to the development of head and neck squamous cell carcinoma (HNSCC)?

What is HPV-16 and HPV-18?

400

What stage of carcinogenesis is characterized by the neoplastic conversion of preneoplastic cells, increased proliferation, and angiogenesis? 

What is progression?

400

Increased urinary frequency, urinary retention, hematuria, lower back pain, and a hard and immovable prostate are all clinical manifestations of what type of cancer?

What is prostate cancer?
400

Which stage is characterized by regional spreading; a growth in tumor size, spread to distant lymph nodes, and effecting more surrounding tissue?

What is stage 3?

500

Certain proteins play a role in cell cycle regulation to ensure healthy DNA, and the synthesis of healthy DNA preceding mitosis such as tumor suppressors. Alterations in these proteins may result in cancer development. Mutations in which genes coding for tumor suppressors causes breast cancer?

What is BRCA1 and BRCA2?

500

What type of cancer originates in glandular epithelial tissue?

What is an adenocarcinoma?

500

What secondary syndrome refers to a group of rare disorders that are triggered by an abnormal immune response to a cancerous tumor that may cause hormonal imbalances, neurological problems, muscle weakness, skin changes, and blood clotting abnormalities. 

What is paraneoplastic syndrome?

500

What kind of cancer do prostate-specific antigen tests and digital rectal exams tests for?

What is prostate cancer?

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