Breast Cancer
I must have this mutation to use trastazumab.
What is HER2?
The mutation erlotinib is targeting.
What is EGFR?
The solvent responsible for paclitaxel hypersensitivity.
What is Polyoxyl35/polyoxylated castor oil?
The non-chemotherapeutic component of FOLFOX.
What is leucovorin?
I am one of the two steroids used concurrently with abiraterone acetate.
What are prednisone and/or methylprednisolone?
I am an oral SERM used in premenopausal breast cancer that can cause fetal harm
What is tamoxifen?
The medications used to prevent myelosuppression from pemetrexed
What are oral folic acid and intramuscular cyanocobalamin?
Recurrence of ovarian cancer less than 6 month after completion of therapy.
What is platinum-resistant ovarian cancer?
I am one of the medications largely responsible for mucositis in colorectal cancer regimens.
What are 5-fluorouracil and/or capecitabine?
The goal for androgen deprivation therapy.
What is slowing disease progression?
I am a hormonal agent that has increased risk of cardiovascular events compared to other hormonal agents.
What is/are anastrozole (aromatase inhibitors)?
The components used in the Calvert Equation for carboplatin dosing.
What are AUC and CrCl based on ABW?
The reason you hold bevacizumab for 28 days before and after surgery.
What is decreased wound healing?
I am used to treat grade 1 diarrhea secondary to irinotecan.
What is loperamide?
This black box warning associated with docetaxel can exacerbate fluid retention.
What is hepatic function impairment?
I am used to treat the hallmark neuropathy associated with paclitaxel and other taxanes.
What are neuropathic pain agents? (Gabapentin, Pregabalin, Duloxetine)
This tells us that TKIs are working, but is also a side effect of TKIs.
What are rashes (dermatologic toxicities)?
I am the cancer marker that can signal efficacy of treatment regimens in ovarian cancer.
What is CA-125?
This medication is used to treat grade 3 diarrhea secondary to chemotherapy.
What is octreotide?
What are nilutamide and flutamide?
I am a cardiovascular black box warning for the SERM tamoxifen, but not raloxifene.
What is stroke risk?
I require aggressive hydration with electrolytes to replete loses and prevent nephrotoxicity.
What is cisplatin?
If you test positive by urine dipstick before treatment, I am what you have too much of in your urine thanks the bevacizumab...
What is proteinuria?
After this many cycles of oxaliplatin, I would be considered higher risk for anaphylaxis...
What are 6 cycles of oxaliplatin?
If you are monitoring hypokalemia, increased blood pressure and fluid retention you are monitoring for what?
Mineralocorticoid Excess