Lung Cancer
What is the treatment for SCLC- limited stage disease?
radiation and chemotherapy
What is the CRAB criteria for Scr?
>2mg/dl
What is a good predictor of a patients risk?
oncotypeDx
What is a natural antiemetic?
cannabinoid
For stage 1 and 2 what therapy is used alone?
surgery
SCLC -extensive disease is treated without?
radiation
observe patient every 3-6 months
What is the end goal for stage 0-III?
cure
What is 1 therapeutic class used for breakthrough nausea?
dopamine antagonists, phenothiazines, or cannabinoinds
What is preferred regimen for advanced stage 3?
FOLFOX
repeat old regimen
botezomib, lenalidomide, and dexamethasone
What are the 2 main endocrine therapy classes used?
SERMs and/or aromatase inhibitors
WBC * % granulocytes(segs + bands)
What role does Leucovorin play in therapy?
enhances activity/efficacy of 5-FU
Most common non small cell lung cancer?
adenocarcinoma
lenalidomide
typically how many cycles of chemotherapy of given?
4-6 cycles every 3-4 weeks
What is the time frame of when filgrastim may be given?
1 to 3 days after chemotherapy
What is drug regimen is given for late-onset of diarrhea after receiving Irinotecan?
Loperamide 4 mg by mouth x 1, then 2 mg by mouth every 2hr until formed bowel movement
What platinum agent is commonly used in this cancer?
carboplatin
What are the three common progenitor cells?
lymphoid, myeloid, and erythroid megakaryocyte
Which aromatae inhibitor is steroidal?
exemestane
What types of iron may be used for iron deficiency?
iron dextran, sucrose, or ferric gluconate
What drugs does FOLFOX consist of?
Oxaliplatin, leucovorin, and fluorouracil