Adrenergic Agonists
Agonism of this receptor acts both peripherally and centrally to decrease BP by decreasing NE release via a negative feedback loop and inhibiting renin release:
What is alpha 2?
This short-acting beta antagonist is metabolized by plasma esterases:
What is esmolol?
ACEIs inhibit the conversion of:
What is angiotensin I to angiotensin II?
Amiodarone works on this phase of the action potential:
What is phase III?
The long sympathetic preganglionic nerve stimulates this organ to release epinephrine:
What is the adrenal medulla?
The treatment of choice in septic shock relating to it's alpha effects over beta effects, resulting in improved control of hypotension:
What is norepinehrine?
This drug causes an irreversible blockade of alpha receptors:
What is phenoxybenzamine?
This dihydropyridine is metabolized by plasma esterases:
What is clevidipine?
Lidocaine exerts it's action by blocking this ion channel:
Alpha 1 adrenergic stimulation leads to this effect on blood vessels:
What is vasoconstriction?
This drug is used as a bridge to pacemaker insertion and will increase HR in the transplanted heart:
What is isoproterenol?
The ratio of alpha to beta receptor blocking seen with IV labetalol is:
What is 1:7?
This direct arterial vasodilator may cause lupus-like symptoms which usually dissipate after discontinuation:
This calcium channel blocker is used to treat ventricular rate in AF/AFlutter:
What is verapamil or diltiazem?
The sympathetic preganglionic nerve fibers exit the spinal cord at this lumbar level:
What is L1-L2?
This class of drugs are contraindicated in the treatment of phenylephrine hypertensive crisis due to risk of pulmonary edema and CV collapse:
What are beta blockers?
Due to this prototypical drug's antagonist effects on both beta 1 and beta 2 receptors, it would be a poor choice to use to lower BP in a patient with RAD:
What is propranolol?
When broken down, this drug breaks down to NO and causes vascular smooth muscle relaxation:
What is sodium nitroprusside?
The treatment of digoxin toxicity is with these 2 medications:
What is phenytoin and magnesium?
The baroreceptors in the aortic arch are innervated by this nerve:
What is the vagus nerve (CN X)?
The IV dose used to treat moderate symptoms of anaphylaxis:
What is 100-200 mcg?
The term used when upregulation of receptors requires more drug to be given for a desired effect:
What is tachyphylaxis?
This is the MOA of the PDE III drugs:
What is inhibition of intracellular cAMP and cGMP?
This endogenous nucleoside disrupts AV node conduction and is beneficial in WPW syndrome:
What is adenosine?
The postganglionic receptors of the PNS, most are cholinergic, except for these glands:
What are sweat glands?