Pressure and Fluid Dynamics
Timing is Everything
End Diastole vs End Systole
Frank-Starling
Wigger's Diagram
100

Blood only moves when this exists.

What is a pressure gradient?

100

Heart sound occurring immediately before IVCT.

What is S1?

100

Time when ventricular walls are thinnest.

What is end-diastole?

100

Increasing EDV increases this.

What is preload?

100

Valve closure producing S2.

What are the aortic and pulmonic valves?

200

If LA pressure is 14 mmHg and LV pressure is 9 mmHg, blood moves in this direction.

What is from the left atrium to the left ventricle?

200

The chamber pressure relationship required to terminate IVRT.

What is LV pressure becomes lower than LA pressure?


200

Time when atria are largest

What is end-systole?

200

The Frank-Starling mechanism increases these two forces.

What are inotropy and chronotropy?

200

The E-wave occurs during this phase.

What is rapid ventricular filling?

300

Immediately after the LV reaches 125 mmHg while the aorta is 90 mmHg, this valve changes state.

What is the aortic valve opens?

300

Which event occurs first?

Atrial contraction

Mitral valve closure

Electrical stimulus in the ventricle

What is mitral valve closure?

300

At this instant preload reaches its maximum.


Answer: What is end-diastole?

300

Why does increasing preload initially improve contraction?

What is reduced actin overlap and increased titin recoil?

300

The A-wave immediately follows this electrical event.

What is atrial depolarization (P wave)?

400

If LV pressure never exceeds aortic pressure, what phase of the cardiac cycle never truly begins?

What is ventricular systole (ejection)?

400

During which phase are ALL FOUR valves closed while ventricular pressure is rising?


What is IVCT?

400

A sonographer measuring LV internal dimension for preload assessment chooses this phase.

What is end-diastole?

400

A ventricle receives excessive preload stretching beyond its limits. Contractility becomes ________.

What is markedly decreased?

400

Name every event between S1 and S2.

  • IVCT
  • Aortic valve opening
  • Ventricular ejection
  • End systole
500

Increasing systemic blood pressure primarily increases this ventricular workload.

What is afterload?

500

During which phase are ALL FOUR valves closed while ventricular pressure is falling?


What is IVRT?

500

The ventricular chamber contains the least blood immediately before this phase begins.

What is IVRT?

500


A patient has severe hypertension but normal preload. Which force rises?

What is afterload?

500

Place these in order:

Aortic valve closes

Mitral valve opens

LV pressure falls below LA pressure

IVRT begins

  1. Aortic valve closes
  2. IVRT begins
  3. LV pressure falls below LA pressure
  4. Mitral valve opens 
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