Neurovasculture Injuries
Quick! You FOOSHed (fell on an outstretched hand) - what artery are you most concerned of being injured?
Radial artery
in rheumatoid arthritis, pain gets better or worse with use?
better with use
pain at base of big toe
(symptom of a disease)
gout
True or False:
Acetaminophen is anti-inflammatory
FALSE
acetaminophen is NOT anti-inflammatory
aspirin & NSAIDs ARE anti-inflammatory
malar rash & discoid rash
SLE
You fell asleep with your arm slumped over a chair and now you can't extend your wrist - what nerve did you injure?
radial n.
the following 4 signs are associated with what type of arthritis?
- joint space narrowing
- subchondral sclerosis
- osteophytes (bone spurs)
- subchondral cysts
osteoarthritis
waiter's tip hand
Erb's palsy (C5, C6 injury at upper trunk)
Reye's syndrome is an ADR of aspirin in kids - what's the one time you WOULD use aspirin in kids?
Kawasaki's Disease
increased alkaline phosphatase levels are associated with increased osteoblastic or osteoclastic activity?
osteoblasts!
You've been biking all around Philly and now your wrists hurt from gripping the handlebars too tight - what nerve did you potentially hurt?
(hint: you may have fractured the hook of your hamate...)
ulnar nerve running though Guyon's canal
(cyclist's palsy)
name the 5 major symptoms of limited scleroderma
CREST
Calcinosis
Raynaud's phenomenon
Esophageal dysmotility
Scleroderma
Telangiectasis
(symptom of a disease)
achondroplasia
MOA of methadone
long-acting mu opioid agonist
(is very potent)
For DEXA scans, what T-score range would be indicative of osteoporosis?
< -2.5
-2.5 to -1 is osteopenia
-1 to +1 is normal
reminder: these numbers are standard deviations!
A posterior hip fracture would injure what big nerve?
sciatic n.
in septic arthritis, if you tap the joint, what will the synovial fluid look like (clear, cloudy, red, etc.)?
cloudy and weirdly thick because its purulent (>50K WBCs)
positively birefringent and yellow under perpendicular light
pseudogout
aka calcium pyrophosphate deposition disease
What's a super common SERM (selective estrogen receptor modulator) and what MSK-specific disease it's used for?
Raloxifene
for post-menopausal osteoporosis
deficiency of glucose-6-phosphate is seen in what disease
Von Gierke's disease
(aka glycogen storage disease type 1)
If you're trying to make a fist, and then most you can do is an OK sign, what nerve is injured AND is the injury proximal or distal?
proximal ulnar n. injury
anti-Smith antibodies are directed against what specifically (don't say Smith) AND are specific to what disease?
directed against snRNPs (small nucleuar ribs-nuclear proteins)
specific to SLE (lupus)
scaly plaques on skin (usually on extremities)
(symptom of a disease)
psoriasis
MOA = microtubule inhibitor (by binding to tubulin)
name the drug AND its major ADR
colchicine
(anti-gout drug)
major ADR: diarrhea
what type of hypersensitivity is Sjögren's syndrome?
type 4 hypersensitivity
is a lymphocyte-mediated autoimmune disorder