Epidemiology & Risk Factors
This percentage of the general population is affected by celiac disease.
What is 1%?
This is the most common GI symptom at presentation.
What is diarrhea (especially in adults)?
Name the first line serologic test for all age groups.
What is IgA tissue transglutaminase (IgA tTG)?
Name the primary treatment for celiac disease.
What is lifelong gluten-free diet? (<10 grams daily)
These two alleles are most commonly associated with celiac disease.
What are HLA-DQ2 and HLA-DQ8?
Name 4 intestinal manifestations of celiac disease.
What are bloating, alternating bowel habits, chronic abdominal pain, chronic constipation, chronic or intermittent diarrhea, GERD, aphthous stomatitis, nausea and vomiting?
Gluten-containing diet should be followed for this amount of time before testing.
What is 2-6 weeks? (at least 3 grams daily- ~1.5 slices of wheat bread)
Name the lab parameter used for dietary adherence monitoring.
What is IgA tTG antibody?
2-8% of patients with this hypogammaglobulinemia have celiac disease.
What is IgA deficiency?
Name 4 extraintestinal manifestations of celiac disease.
What are iron deficiency anemia, osteoporosis, recurrent miscarriage, transaminitis, amenorrhea, arthritis/arthralgia, fatigue, delayed puberty, depression, dermatitis herpetiformis, epilepsy or ataxia, failure to thrive, peripheral neuropathy, recurrent miscarriage, repetitive fractures, short stature, unintentional weight loss, and dental enamel defects?
Name the serologic test used for patients with IgA deficiency.
What is IgG DGP (deaminated gliadin peptides)?
Name 3 gluten containing grains.
What are barley, rye, and wheat?
This autoimmune condition in children shows 3-8% celiac prevalence.
What is DM I?
Use 3 dermatologic morphology terms to describe the blistering rash associated with celiac disease.
What is multiple intensely pruritic papules and vesicles in grouped (“herpetiform”) arrangements?
No-biopsy diagnosis in pediatric patients is considered if IgA tTG is this many times normal.
What is 10 times?
Prophylactic administration of this immunization is recommended for all adults.
What is pneumococcal immunization?
This chromosomal disorder is linked to an 8% celiac disease prevalence.
What is Down Syndrome?
Name 3 of the 6 classic clinical manifestations of celiac disease.
What are diarrhea, abdominal pain, bloating, malabsorption, unintentional weight loss and failure to thrive?
This is used to confirm diagnosis after positive serology.
What is EGD with small bowel biopsy?
Name one app recommended by the Celiac Disease Foundation that you can recommend to patients.
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