The Cell Cycle
What is happening during the G phases? (G1 and G2)
the cell is getting bigger collecting N,P, O
Why do elephants have less chance of cancer than humans?
They have many copies of P53, humans only have 1
How many pairs of chromosomes are in each of our cells? (Article)
23 pairs
What has to be broken (not working) in order for a cancer cell to duplicate?
P53
Part of the cell that keeps DNA safe.
Nucleus
During what phase are new DNA chromosomes created?
S phase (Synthesis of Genetic Material)
On our 'S-phase Graphic Organizer', what type of mutation got past our P53(c)?
Substitution mutation
Genes contain codes for proteins, the codes are made of bases A-T and ?-?
(kinesthetic model, article, simulation guidance)
G-C
What is a 'substitution mutation'?
(S-phase Graphic Organizer, Simulation Guidance)
When the base pairs match up INCORRECTLY during s-phase.
A single strand copy of DNA
mRNA
During which phase does the cell actually SPLIT?
M phase (mitosis)
P53 is made up of how many base pairs? (article)
18,000
What breaks apart the DNA double helix for copying?
(S-phase Graphic Organizer)
Helicase
Who has more chance of cancer? A short or tall person?
Tall Person
The part of the cell where proteins are made.
Ribosome
What do N, P, and O stand for?
Nutrients, Proteins, Organelles
If a strand of DNA with an ERROR is checked by P53(c), what type of cell will be produced?
(S-phase graphic organizer)
Damaged Cell (cancer cell) (cell with mutation not found)
DNA is copied into RNA; when this happens the base code T changes to ??
(kinesthetic model, article)
U
WHY does a tall person have more chance of cancer than a short person? (3 part)
A tall person has more cells, which means more cell division, which means higher chance of mutation.
P53 has 375 ----- ----- that make it up!
Amino acids
Draw the cell cycle, while explaining how a CANCER cell can be created.
Draw @ Board
Give one example of how P53 can prevent a cancer cell from forming.
If P53 detects an error, during the cell cycle, it will either correct the error or destroy the cell.
Does all of the RNA code get used before it leaves to the ribosome?
(article, kinesthetic model)
NO
Why does an older person have a higher risk for cancer than a younger person? (2 part)
An older person has had a higher number of cell divisions over time, and therefore has a higher chance of cell mutation.
Eye color & hair color (segments of DNA that code for a certain protein) are examples of what?
Gene(s)