Immunology, of course
Vaccines
More Vaccines
Diagnostics
More Ch 18
100

As opposed to active immunity, the effectors of this kind of immunity will not be created by the host itself.  

What is passive immunity?

100

This type of vaccine is very safe, but also requires multiple boosters because it only has a few immunogens from the microbe.

What is an acellular/subunit vaccine?

100

The conjugate vaccine is extremely helpful in protecting against bacteria that have this virulence factor.

What is a capsule?

100

These types of antibodies can be used for diagnostics or treatments.

What are monoclonal antibodies?

100

Low specificity can result from this phenomenon, which means there are similar epitopes on different antigens.

What is cross-reactivity?

200

As opposed to natural immunity, this kind of immunity introduces a medical product to elicit or provide protection. 

What is articifial immunity?

200

Attaching a protein to this type of molecule will give the molecule's epitopes immunogenicity.

What is polysaccharide?

200

This is what you should say if someone tells you vaccines cause autism.

What is "No, they don't"?

200

In a direct test, this molecule is labeled with a reporter enzyme and is designed to bind directly to an target.

What is a monoclonal/reporter antibody?

200

These are two examples of in vivo diagnostics using the human response rather than kits.

What are allergy testing and tuberculin skin testing?

300

This is one example of artificial passive immunity.

What is mAb or pooled plasma?

300

This kind of vaccine can potentially cause infection in immunocompromised patients.  

What is live attenuated vaccine?

300

This is what happens when people stop getting vaccinated for a disease that is almost eradicated.

What is an increase in cases?

300

In an indirect ELISA, this is typically the unknown element.

What is the patient serum? (containing unknown antibodies)

300

COVID tests that look for past infections may be using this kind of ELISA looking for this molecule.

What are indirect ELISA and anti-coronavirus antibodies?

400
This is the type of cell that creates mAb....not just any ordinary plasma cell, but fused to this kind of cell for immortality.

What is a hybridoma, made by fusing to myeloma?

400

This is the kind of vaccine that provides the best cell-mediated immune response.

What is live attenuated?

400

This is the process of protecting the few by vaccinating the many.

What is herd immunity?

400

This is what a titer allows us to do with indirect ELISA testing.

What is to quantify antibody load in a patient?

400

This kind of ELISA test looks for current infections (not the molecular one...the other one)

What is direct ELISA or antigen test?

500

This is how we create anti-human-antibody antibodies.

What is injecting a human constant fragment into an animal to activate anti-human-antibody B-cells?

500

This kind of vaccine can be created by removing genes for certain virulence factors from a microbe.

What is live attenuated vaccine?

500

Not a traditional vaccine, this type of therapy modifies T-cells from a person and then gives them back to the patient.

What is chimeric antigen receptor (CAR) T-cell therapy?

500

If specificity is low in a diagnostic test, we may have false these.

What is false positive?

500

This is the benefit of vaccination over variolation.

What is safety? (using vaccinia vs. variola means less vaccine side-effects)

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