Key term
Air Exchanges
new air replacements
Asepsis
the abasence of pathogenic microorganisms
Clean room
an ISO-classified room (or two-room configuration of a cleanroom area) in which the concentration of airborne particles is controlled to meet a specified air-born-particulate cleanliness class to prevent particle and microbial contamination of CSPs
Anteroom
an ISO Class 8 room or area immediately before the buffer room in which hand washing, hygiene, and garbing are done and supplies and ingredients are gathered between the pharmacy department and the classroom or buffer area
Aseptic hand washing
a more aggressive soap and water hand washing procedure, followed b use of an antiseptic agent before donning sterile attire
Aseptic technique
the manipulation of sterile products and devices to avoid contamination by disease-causing organisms; includes cleanroom protocols and hand-washing and gowning procedures
Disinfectant
a chemical agent such as sterile 70% IPA used on inanimate surfaces and objects to destroy fungi, viruses, and bacteria, but not necessarily their spores
Bactrim
a small, single-celled microorganism that can exist in 3 main forms depending on type: spherical, rod-shapped, and spiral
Compounded Sterile Preparation
a medication prepared with aseptic technique in a sterile, cleanroom facility
Critical Site
the part of the syringe and/or needle at risk for contamination by touch or airflow interruption
HEPA
a device used to filter over 99% of particulate matter from the air to establish an aseptic environment in which to prepare CSPs
In-Line Filter
a device used in the IV line to remove contaminants such as glass, fibers, bits of rubber, and bacteria from IV fluids
Autoclave
a device that generates heat and pressure to sterilize objects instruments, and measures vessels
Filtration
funneling of a liquid or gas through filters, or mesh screens with minute holes too small for biological and chemical contaminants to pass through
Injection Port
a connector on the IV tubing which allows the injection of IV fluid or medication other than that in the current IV bag to be infused into the patient’s vein
Zone of turbulence
wherever the unidirectional filtered air meets resistance or blockage, particularly between the DCA and compounding technician; also the area at the edges of the compounding counter where the horizontal airflow meets the buffer room air
IVPB
a small-volume parenteral (SVP) infusion (50, 100, 250 mL) containing medications attached to a primary LVP IV solution
Drip chamber
the small, open space just below the spike adaptor where the drops of fluid from the IV bag into the tubing are counted by the nurse to determine the flow rate of the IV solution
Auxiliary Clamp
slide clamp used to completely stop the IV solution from flowing
ISO
an air quality classification from the International Organization for Standardization measures the amount of particulate matter in room air; the lower the ISO number, the less particulate matter is present in the air
Buffer room
an ISO class 7 or cleaner area where the PECs are physically located
Sepsis
when an infection is so threatening to the body that the immune system begins to attack the body’s own blood vessels and organs causing inflammation, leaky vessels, organ failure, and septic shock
Horizontal Laminar Air Flow Workbench
used to prepare IV drug admixtures, nutrition solutions, and other parenteral products aseptically
LVP (Large Volume Parenteral)
IV solutions of more than 250 mL that may contain medications, nutrients, or electrolytes
Epidemic
a regional widespread contagious disease