Chapter 2: Drug Design, Testing, Manufacturing, and Marketing

Drug Names

100

Each drug has this many names

What is 3 names

200

The drug company gets to create this name for the drug; also known as the brand name or proprietary name.

That is the trade name

300

The IUPAC assigns every drug this... once it's discovered or designed

What is the chemical name

400

The drug company, together with the USAN Council determines one of these for each chemical name

What is a generic name

500

The meaning of the abbreviation IUPAC

What is the International Union of Pure and Applied Chemistry

Testing of New Drugs

100

The chemical analysis of a drug done in a laboratory in test tubes

What is in vitro

200

Involves using mathematics to describe the mechanism of action by which the drug produced its effects based on time and dose.

What is pharmacodynamics

300

Testing carried out in animals or humans.

What is in vivo

400

Also known as human testing and consists of 3 phases.

What are clinical drug trials

500

The relative margin of safety between the dose that produces a therapeutic effect and the dose that produces a lethal effect in animals. The higher, the better!

What is the therapeutic index 

Abbreviations

100

NDA

What is New Drug Application

200

ED₅₀

What is median effective dose

300

IND

What is Investigational New Drug

400

NDC

What is National Drug Code

500

TI

What is therapeutic index

Pharmacology Words

100

Substances that are inactive in the body and used by drug companies as fillers and binders to create tablet shapes which can affect bioavailability

What are inert ingredients

200

Happens when the FDA removes all of a drug or certain batches of a drug from a market because of manufacturing defects.

What is a drug recall

300

Happens when the FDA removes  a drug from the market due to adverse drug effects or events

What is a (drug) withdraw

400

The study of the chemical structures of drugs and their effects at the molecular level within the cell... thanks computers!

What is molecular pharmacology

500

It's a drug that has undergone molecular manipulation

What is an isomer

Pharmacology Hodgepodge

100

The knowledge of how the genetic makeup of different people affects their responses to drugs

What is pharmacogenetics

200

The use of information in the patient's human genome to customize a drug treatment that matches that patient's genetic profile. 

What is pharmacogenomics

300

The portion of the drug that, after absorption, is actually available to produce a therapeutic effect

What is bioavailability

400

The first recombinant DNA technology drug to be approved by the FDA.

What is human insulin (Humulin)

500

The time required for the drug level in the blood to decrease from 100% to 50%

What is half-life