9A
9C
9B/9D
9E/9F
100

There are 3 black sheep and 7 white sheep. What is the allele frequencies for wool colour?

Black allele - 30%

White allele - 70%

100

Define 'bottleneck effect'

The bottleneck effect occurs when a large portion of a population is wiped out by a random event, such as a natural disaster

100
What are the four conditions required for natural selection 

Variation, selection pressure, selective advantage, heritability 

100

What is the selection pressure that creates 'superbugs'?

Exposure to antibiotics 

200

State the difference between a silent and a missense mutation

 Silent mutations do not change the amino acid coded, while missense mutations do

200

What is the key difference between genetic drift and gene flow?

Genetic drift is random, gene flow is not

200

How do scientists know that two populations have speciated?

They can no longer produce viable, fertile offspring when they breed

200

What is the difference between natural selection and selective breeding?

Human preferences act as the selection pressure instead of random environmental factors

300

What is aneuploidy? Provide an example.

A chromosomal abnormality which results in the wrong number of chromosomes. e.g. down syndrome has one extra chromosome

300

Explain how interbreeding affects genetic diversity of a population 

Interbreeding can introduce new alleles into a population, increasing genetic diversity 

300
What is the difference between allopatric speciation and sympatric speciation? Provide examples.

Allopatric speciation is when a population is separated by a physical barrier, creating new pressures e.g. a mountain range forming. Sympatric speciation is when a population speciates in the same environment with different pressures e.g. pH of soil for trees

300

What is the difference between antigenic drift and antigenic shift?

Antigenic drift is the gradual change of antigens on the surface of viruses, whereas antigenic shift is a sudden change in surface antigens

400

Why are frameshift mutations more severe than point mutations?

Frameshift mutations are the addition of deletion of a nucleotide, which shifts the entire codon reading frame and all amino acids past that point, significantly affecting protein structure

400

Explain the difference between immigration and emigration on the genetic diversity of the ORIGINAL population 

Immigration is when new individuals enter the population, bringing new alleles and increasing genetic diversity. Emigration is when individuals leave the population, removing alleles and decreasing genetic diversity 

400

What can be a disadvantage of successful natural selection in a population?

If certain traits are selected for, it may decrease the genetic diversity of the population, meaning they are less likely to survive any new pressures.

400

Provide two human-induced reasons for antibiotic resistance

Not finishing antibiotic treatments, using antibiotics when you do not need to, widespread prescription by doctors 

500

What is a 'block mutation' and in what process do these usually occur?

It is when segments of DNA are deleted, duplicated or rearranged on the chromosome. This happens during meiosis

500

Why are smaller populations more susceptible to extinction? 

Smaller populations typically have less genetic variation. If genetic drift occurs, they may not have the diversity to survive their environment 

500

You are given a 4-mark question asking to explain how natural selection occurred in Darwin's finches. Answer it!

The finches living on the islands had natural genetic variation, including variation in alleles that coded for beak type (1). As the birds lived on different islands, they were exposed to different food sources, which acted as a selection pressure (1). Birds that had beaks that were suited to the food on the island had the selective advantage and were more likely to survive (1) and therefore pass on their alleles to the next generation and change the traits of the population (1)

500

Explain why a new flu vaccine is required every year

The flu virus undergoes antigenic drift, where the antigens on the surface slightly change each year. This means our memory cells will not recognise it, and a new vaccine is required 

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