Side Effects
Bone marrow suppression causes what changes in labs?
Decreased WBC, neutropenia, thrombocytopenia, low platelet count, anemia
N/V can be prevented by?
Antiemetic prior to starting drug
What can IV extravasation cause?
Severe tissue damage
What are some nursing assessments that are important to identify thromboembolic events?
Assess lung sounds, SOB, pain/edma in calf, S/S CVA, (FAST)
What is the priority nursing action if a patient develops a low-grade fever?
Tylenol, supportive care
What are some S/S of peripheral neuropathy?
Weakness, tingling, gait disturbances
What is the priority nursing action for pain at the IV site during chemo?
Stop infusion immediately and assess
Prior to receiving a live vaccine the patient should?
Talk to PCP/not get vaccine
Bone density testing is required for which hormonal therapy?
leuprolide
AMS is a common and reversible S/E, what assessments will you perform?
Assess for A/OX4, any confusion
Cardiac toxicity is caused by?
ANTI TUMOR (CYTOTOXIC) ANTIBIOTIC: Doxorubicin
What is the priority nursing action if a patient experiences hematuria during chemotherapy?
Expected finding with cyclophosphamide, monitor blood in urine, increase fluids to 3L/day
What labs will the nurse monitor for patients on drugs that negatively impact kidney function?
BUN, creatinine, GFR
Tamoxifen can lead to which type of cancer?
Endometrial
You are concerned about Neurotoxicity; what assessments will you perform?
Monitor for confusion, ataxia, paresthesias, aphasia; (reversible)
Fatal anaphylaxis is most common in
asparaginase
What important education for drugs that suppress bone marrow would you provide your pt?
Avoid sick contacts, avoid crowds, report s/s infection immediately, labs CBC, especially neutrophils
If a drug affects the liver negatively, what education will you provide to your patient?
S/S liver failure, abd pain, bloating, jaundice, pale stools, dark urine, avoid ETOH and get liver function checked, may need decreased dose
Leuprolide can cause multiple side effects; List 3
Hot flashes, ED, decreased libido, gynecomastia, decreased bone density, dysrhythmias, pulmonary edema, disease flare
Interferon is CONTRAINDICATED in which disease processes?
COLITIS, PANCREATITIS, SUICIDAL THOUGHTS (depression)