5-HT3RAs
This agent has a significantly longer half-life than other agents in its drug class, allowing for delayed CINV prevention
What is palonosetron?
This agent is a prodrug that is converted into another agent in the same drug class
What is fosaprepitant?
This atypical antipyschotic has demonstrated benefit as an adjunct for high-risk CINV
What is olanzapine?
This agent can penetrate the blood brain barrier and has purely glucocorticoid activity
What is dexamethasone?
Area in the brain with receptors for various neurotransmitters and activates the vomiting center in the medulla
What is the chemoreceptor trigger zone (CTZ)?
Maximum duration of action for the transdermal patch formulation of granisetron
What is 7 days?
This agent's oral formulation requires redosing on days 2 and 3 post-infusion
What is aprepitant?
This agent has additional benefit for promoting gastric motility
What is metoclopramide?
Maximum duration of wear for scopolamine transdermal patches
What is 72 hours?
This pathway causes nausea/vomiting due to irritation of the GI mucosa from trauma or medications
What is the peripheral pathway?
Agent of this drug class with the lowest risk of QTc prolongation
What is palonosetron?
This agent is only available as combination products with palonosetron
What is netupitant?
This atypical antipsychotic can be used for both prophylaxis and treatment of PONV
What is amisulpride?
True or False: A patient receiving high dose of hydrocortisone as part of their cancer regimen can skip dexamethasone prophylaxis
What is True?
This anesthetic agent can be used in TIVA to reduce baseline risk of PONV
What is propofol?
This agent requires avoidance in renal dysfunction
What is granisetron?
Minimum dosing interval for rolapitant, due to its prolonged half-life of 7 days
What is 2 weeks?
Preferred route of administration for promethazine, due to risk of tissue damage otherwise
What is deep tissue intramuscular?
Benzodiazepines are primarily indicated for this CINV classification of nausea/vomiting
What is anticipatory nausea/vomiting?
This drug class, commonly used in both CINV and PONV, can directly stimulate the chemoreceptor trigger zone (CTZ) to induce nausea/vomiting
What is opioids?
Max dosage for IV administration of ondansetron
What is 16 mg?
A patient with an allergy to this substance may want to avoid taking aprepitant emulsion
What is soybean?
Droperidol has a Black Box warning for this complication
What is QTc prolongation?
Due to drug-drug interactions, you should consider decreasing the dexamethasone dose when given concomitantly with this other antiemetic
What is aprepitant?
Rather than a risk factor, this patient habit is protective against experiencing CINV
What is frequent alcohol consumption?