Frederick Griffith
The microorganism that he used to study.
Streptococcus pneumoniae
Instead of performing the transformation experiment in mice, they did this.
Grew cells in culture
They used these organisms in their experiments
Bacteriophages
You can use this to separate cellular compartments by weight
Cesium Chloride Gradient and Centrifugation
This is what DNA stands for.
What is deoxyribonucleic acid?
The wild type that he studied has this around it.
polysaccharide capsule
The result of S cell extract + live R cells + RNAse
S cells (transformation)
Radioactive sulfur is detectable in these.
In this model, we expect to observe one completely new helix and one parental helix.
Conservative replication
The nitrogenous bases are divided into these two groups.
What are purines and pyrimidines?
When he injected the S type into the mouse, this happened.
It died.
The result of S cell extract + live R cells + Protease
S cells (transformation)
Radioactive phosphorus is detectable in these.
DNA
Cell debris will stay in this layer after centrifugation
Top layer
The position on the sugar ring where it binds to nitrogen.
What is 1' position?
When he injected the R type into the mouse, this happened.
The mouse lived.
The result of S cell extract + live R cells + DNAse
R cells (no transformation)
This is what happens when T2 injects its genes into the host cell.
New phages form and cell bursts.
In this model, we expect to see blocks of parental and daughter materilas in both strands.
Dispersive replication
The name of the bond that forms between sugar and base.
Beta-n-glycosidic bond
It protects the bacteria from an animal's immune response.
Polysaccharide capsule
They did this to eliminate the fat.
Ultracentrifugation
The name of the blender they used.
Waring blender
This is why they grew E. coli in 14N medium.
To incorporate radioactivity into its DNA.
The form of DNA that Watson and Crick discovered.
B form or right-handed DNA