Testing Testing
You should never use this for an indication of cure as it can remain positive for >8 weeks post infection
What is labratory testing?
This risk factor for C Diff, cannot be avoided if you need care and is a big reason for increasing colonization rates
What is exposure to healthcare facilities?
These two toxins that are associated with CDI damage and inflammation (Two answers)
What are Toxin A and Toxin B?
What is diarrhea?
This laboratory test for CDI is sensitive, but not specific, meaning that it cannot distinguish active infection from colonization
What is a C Diff NAAT?
This protective hospital policy is enacted in patients with C Diff and means you probably shouldn't care for them without proper gear
What are contact precautions?
This is the brand name of the MAB that targets Toxin B and is sometimes used as an adjuvant therapy for recurrent CDI
What is Zinplava (Bezlotoxumab)?
This class of medications can often be a confounding factor in diarrhea and should probably be discontinued before you order C Diff tests
What are laxatives?
This laboratory test (that reflexes at Froedtert) is specific, but not sensitive and can help distinguish active CDI vs colonization
What is a toxin EIA?
This class of medications got slapped with an FDA Drug Safety Communication in 2012 based on post-marketing surveillance that suggested increased risk of CDI was associated with their use
What are PPIs?
Severe C. Diff is classified as a WBC greater than this number and a SCr greater than this number (two answers)
What is a WBC >15,000 and a SCr >1.5
This highly effective "crappy" procedure can be recommended after 2 CDI reoccurrences
What is a fecal microbiome transplant?
This combination of NAAT and ELISA tests is considered an "Inconclusive result" and should probably warrant an ID consult
What is NAAT positive and EIA negative?
This antibiotic, that works by inhibiting protein synthesis by binding to 50S ribosomal subunit, is attributed to a high risk of developing CDI
What is clindamycin?
This is the term that describes patients who are colonized with toxigenic C diff but do not produce toxin
What are asymptomatic carriers?
This is what you should "run" before any patient tries to leave the hospital on fidaxomicin
What is a test script?
This finding, often seen on colonoscopy, is highly suggestive of CDI and looks like gross pimples on your colon
What is pseudomembranous colitis?
This protective mechanism of C Diff is one of the reasons that it's so difficult to get rid of
What is ability to form spores?
This is the only indication for which fidaxomicin is not recommended as first line by the IDSA
What is fulminant C Diff?
This is the class of antibiotics to which fidaxomicin belongs
What are the macrolides?