Stimulants/
Depressants
Depressants
High potential for abuse, tolerance, and dependence
What is amphetamine?
results in Myasthenia Gravis
What is lack of ACh receptor sites?
MOA: suppress calcium influx
What are Succinimides?
converts brain cells to dopamine
what is levodopa?
Medication that causes urine to have a brownish orange discoloration or darkened.
What are Catechol-O-Methyltransferase Inhibitors? tolcapone and entacapone
Long-acting barbiturates (CSS IV) control seizures in epilepsy
What is phenobarbital?
edrophonium (Tensilon)
What is Acetylcholinesterase Inhibitors?
Warn patient not to D/C abruptly to prevent status epilepticus
What is phenytoin (Dilantin)?
Parkinson’s is an imbalance of these neurotransmitters
What are dopamine (DA) and acetylcholine (ACh)?
Stimulate the brainstem and the cerebral cortex to stimulate respiration
What is xanthines, theophylline (Theo-dur)?
Should not be taken in the evening or before bedtime insomnia
What is amphetamine-like drugs, methylphenidate (Ritalin)?
Administer 30 min before meals if difficulty chewing; best absorption on empty stomach
What is pyridostigmine (Mestinon)?
Phenobarbital Therapeutic serum level: 20-40 mcg/mL
What is 20-40 mcg/mL?
Medication that prolongs the action of levodopa
What are MAO-B Inhibitors, selegiline HCL (Eldepryl)?
For benzodiazepine overdose
What is flumazenil (Romazicon)?
Works by increasing the action of the inhibitory neurotransmitter GABA (the ”chill” NT)
What are benzodiazepines, alprazolam (Xanax)?
First-line treatment for MS – can slow disease progression and prevent relapses
What is immunomodulators?
Enhance action of GABA
What are barbiturates, benzodiazepines, gabapentin (Neurontin)?
Educate patient: avoid alcohol, cigarettes, caffeine, aspirin, hard candy, gum, ice chips for dry mouth, sunglasses for photophobia
What are anticholinergics?
Type of drug that inhibits Vitamin K and increases the loss of folate (folic acid) in pregnant patients.
What are anticonvulsants?
Monitor for respiratory depression (slow, irregular breathing patterns)
What is non benzodiazepines, zolpidem tartrate (Ambien)?
Assess for serotonin syndrome with this medication
What is cyclobenzaprine (Flexeril)?
Grapefruit (juice) can cause toxicity with this medication.
What is carbamazepine (Tegretol)?
Drugs that are used to treat Parkinson’s
What are Anticholinergics, Dopamine replacements, Dopamine agonists, (MAO-B) Inhibitors, COMT Inhibitors?
tyramine foods taken with MAO-B Inhibitors causes this condition.
What is hypertensive crisis?