Basics of Clotting
This vitamin is required for clotting factor synthesis.
What is vitamin K?
This protein is converted into fibrin to stabilize the clot.
What is fibrinogen?
This inherited disorder leads to prolonged bleeding due to missing clotting factors.
What is hemophilia?
This lab value measures platelet count.
What is CBC (complete blood count)?
The first priority when a patient with a bleeding disorder sustains trauma.
What is apply pressure/stop the bleeding?
This element, carried in the blood, is necessary for clot formation.
What is calcium?
This enzyme converts fibrinogen to fibrin.
What is thrombin?
This acquired condition involves widespread clotting and bleeding simultaneously.
What is DIC (disseminated intravascular coagulation)?
This test measures the extrinsic pathway and is used to monitor warfarin.
What is PT/INR?
Patients with clotting disorders should avoid this over-the-counter drug that inhibits platelets.
What is aspirin (ASA)?
The process of stopping bleeding through vascular spasm, platelet plug, and coagulation.
What is hemostasis?
The intrinsic and extrinsic pathways both lead to this “common pathway.”
What is activation of factor X (Xa)?
This genetic condition increases the risk for venous thrombosis.
What is Factor V Leiden mutation?
This test measures fibrin degradation products, elevated in DIC and clot breakdown.
What is a D-dimer?
This antidote reverses warfarin overdose.
What is vitamin K?
These cell fragments are essential for forming the platelet plug.
What are platelets (thrombocytes)?
This test evaluates the intrinsic pathway and is prolonged with heparin therapy.
What is aPTT?
A lack of platelets is called this condition.
What is thrombocytopenia?
This lab value should be checked before giving heparin.
What is aPTT?
This antidote reverses heparin overdose.
What is protamine sulfate?
The medical term for a blood clot that travels through the bloodstream.
What is an embolus?
This clotting factor deficiency causes Hemophilia A.
What is factor VIII?
This autoimmune disorder often involves antibodies against platelets.
What is ITP (immune thrombocytopenic purpura)?
Low fibrinogen on labs may suggest this life-threatening condition.
What is DIC?
A patient with DIC may require these two simultaneous treatments.
What are heparin (to stop clotting) and blood products (to replace factors/platelets)?