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How Alzheimer's disease occurs?
Alzheimer's disease occurs by the accumulation of hard, insoluble amyloid plaques between neurons. Neurofibrillary tangles cause microtubule to collaspe. During the progress, brian tissue shrinks but its ventricles enlarge. Short-terms memory begins to decline when the cells in the hippocampus degenerate. As Alzheimer's disease spreads through the cerebral cortex, judgment worsens, emotional outbursts may occur and langugae is impaited. Its advancement also lead to the death of more neurons and subsequent changes in behavior. In the final stage, memory worsens and may become almost non-existent.