Mutated genes involved in the development of colorectal cancer
Tumor suppressor gene that inhibits cell growth
What is APC gene?
Tested for with FBOT Test
Waht is blood in stool?
Complications related to tumor
What are bleeding, bowel obstruction, bowel perforation, fistula formation to surrounding organs or abdominal wall?
Tumor suppressor that inhibits the cell cycle
What is TP53 gene?
Physical Appearance
Complications related to surgery
What are bleeding, infections, anastomosis leaks after resection, hernias?
Oncogenes that induce cell proliferation?
What are
BRAF
PIK3CA
Diarrhea, constipation, changes in stool shape
What are changes in bowel habits?
Oncogene that induces cell invasion and metastasis
What is KRAS gene?
Fatigue, weight loss, vomiting, abdominal discomfort
What are common symptoms?
Tumor suppressor gene that inhibits tumor metastasis
What is SMAD4?
Increased level of this tumor marker
CEA (Cancerembryonic antigen)