These corneas don't have good jeans
These corneas have even worse jeans
Mission Impossible: The Athens Protocol
Odd diseases
Fun Stuff
100
Disease and stains on pathology?
Avellino (granular type 2)
Hyaline (Masson trichrome) AND Amyloid (Congo red)
100
What is the dystrophy?
BONUS (+200): What is the stain?
Schnyder
Oil red O and Sudan black B
100
Name 2 systemic conditions and 2 ocular diseases associated with keratoconus
BONUS (+200): Give all 5 ocular in book
Systemic -> Atopic, Down, Ehlers Danlos, Osteogenesis imperfecta, Sleep apnea
Ocular -> Vernal, Floppy eyelids, ROP, RP, LCA
100
What is the disease and what is the lab to order?
BONUS (+100): Definitive diagnosis
Wilson (or PBC, etc.), serum ceruloplasmin for Wilson
Liver biopsy
100
A girl must answer. Who did Tom Brady play for most of his career?
Patriots
200
Name the three dystrophies that are autosomal recessive and name 2 subtypes of the first one in the mnemonic
Gelatinous (Mulberry, Kumquat, stromal, band K), macular, CHED2
200
How do you tell the difference between Reis-Bucklers and Thiel-Benke on electron microscopy?
BONUS (+200): List in order of recurrence in graft; granular, lattice, reis-bucklers, macular
Thiel-Benke has curly fibers
Rude Little ga- er Green Men
200
Name 4 eponyms for signs of keratoconus
BONUS (+200): 2 types of scarring
Munson, Rizzuti, Fleischer ring, Vogt striae
REticular and nummular
200
You are consulted for an NAT exam. The 3 other kids have the impeccable behavior of the Robertson kids so you highly doubt that it is NAT. What will you look for, and if it is this disease, how do you treat it?
Blue sclera, oral bisphosphonates
200
A guy must answer. What movie in 1995 features Paul Rudd and Alicia silverstone (Cher), and is about rich high schoolers in Beverly Hills?
Clueless
300
Gene for this dystrophy (not granular)
BONUS: What antigen is measured on ELISA stain
CHST6
BONUS: Keratan sulfate
300
Name the dystrophy. What other condition must be considered if this is in 1 eye?
BONUS: What percentage have elevated IOP? Must be within 2%
PPCD, ICE syndrome
14%
300
According to the book, what is the significant I-S ratio?
BONUS (+300): What are the 4 parameters of the Belin ambrosio criteria.
1.2
Anterior and posterior curvature, thinnest pachy, CDVA
300
What enzyme is deficient?
BONUS (+300): Lesion in vitamin A deficiency that is in similar area on conj.
Homogentisic acid oxidase
Bitot spot
300
What is JD's love interest and co-resident named in Scrubs?
Elliot
400
Gene for early-onset of this disease?
BONUS: Name the 4 stages in the book
COL8A2
1) Corneal guttae
2) Endothelial decompensation and stromal edema
3) Bullous keratopathy
4) Scarring, subepi fibrosis, peripheral superficial NV
400
Which dystrophy is associated with pseudoxanthoma elasticum, limbal dermoid, decreased corneal sensation, and atopy?
BONUS: What does PPPCD stand for?
Fleck
Punctitiform and polychromatic pre-Descemet corneal dystrophy
400
Explain how to do Dresden protocol cross-linking if your pachy is 410.
BONUS (+200): What is it called if you want to do topo-guided PRK with your CXL?
Remove epi, hypotonic riboflavin before UVA every 2 minutes for 30 minutes, slit lamp for fluorescence, pachy, then UVA for 30 minutes, BCL
BONUS: Athens protocol
400
Orange tonsils and arcus with enlarged liver, spleen, and lymph nodes
BONUS (+400): This disease and Bassen-Kornzweig would lead you to order what lab study?
Tangier disease
Lipid panel for hypolipoproteinemia
400
Name both of Dr. Tsai's techs. Can't be a PGY-4
Janie and Alyssa
500
Dystrophy that is like corneal plana AND why is it maybe not a dystrophy?
BONUS (+500): Name some other findings in this disease
Posterior amorphous corneal dystrophy; mesodermal dysgenesis
BONUS: Iris processes, pupillary remnant, iridocorneal adhesions, corectopia, etc.
500
Patient has this and dermatochalasis. Name the syndrome
BONUS (+300): 3 other possible findings.
Meretoja; lagophthalmos, cranial nerve palsies, dry skin, pendulous ears
500
Kid comes in with a globular cornea. What systemic disease specifically are you worried about?
Ehlers-Danlos Type VI
500
Describe the different types, name two genes, and give 2 ocular associations and 2 systemic findings
BONUS: What is the difference between keratectasia and congenital anterior staphyloma?
Peters; cornea-iris vs lens-cornea; PITX1 and FOXC1 (or others), CYP1B1; glaucoma, PFV, microcornea, RD; cardiovasular, hearing, dysmorphic face, heart defects, intellect, etc.
BONUS: Keratectasia dose not have a uveal lining and CAS does
500
Who is Jim's office romance prior to getting engaged to Pam?
BONUS (+1000): Capital of Vermont according to Andy in the Office?
Karen Filepelli