Acronyms
A program first research RCN, which means _
What is Research Candidate Nomination?
Buckbeak - small molecule investigated
What is DCA? (dichloroacetate)
CD45
Leukocytes
Xuri
Rocking bioreactor
When a program reaches DCN, which stands for _, it kicks off _ activities
What is Development Candidate Nomination? What are IND enabling activities?
bb2121/bb21217 - target and difference between
What is multiple myeloma? What is added PI3K inhibitor (bb007)?
CD3
T cells
Lovo
Cell washing
The name of the company prior to bluebird bio
Genetix Pharmaceuticals (incorporated in 1992)
A process ready for manufacturing scale first needs to undergo TT, which stands for _
What is technology transfer?
bbT369 - target & unique technology used
What is B cell Non-Hodgkin's lymphoma? What are dual CAR & cbl-b edit?
CD19
B cells
Sepax
Microbead labeling & RBC lysis (with ZAPR reagent)
Jeff Walsh (former CFO) wager on first approval
Shaving his head
A large study can be reduced in number by utilizing DOE, which stands for _
What is design of experiments?
MAGE-A4 - general intended target & part of technology used
What are solid tumors? What is TCR?
CD56
NK cells
CliniMACS Plus
Cell isolation
Nick Leschly's vow on our first approval, extended to the full company
bbb themed tattoos
Integrating control and mitigating risk is accomplished by using the principles of QbD, which stands for _
What is Quality by Design?
MUC16 - intended target
What is ovarian cancer?
CD11c
Dendritic Cell
CliniMACS Prodigy
Fully enclosed CAR-T manufacturing
The running joke about Nick Leschly and bananas
He doesn't know what they cost...