Symptoms
The main body system implicated in CJD.
The nervous system
Name of newest testing method for CJD.
RT-QuIC
Specimen type which poses the greatest risk to lab staff (according to AHS 2015).
CSF
Name of secondary protein structure differentiates normal PrP from abnormal PrP
Beta-pleated sheets
Most common type of CJD
What is sCJD (sporadic)
One main symptom of CJD
Severe mental deterioration or Dementia
Myoclonus or Involuntary muscle movement
Name of testing method used to determine presence of Tau protein.
ELISA
Label on a specimen with suspected CJD
"CJD Precaution"
Mechanism of abnormal prion proteins spreading in the body
Induce normal prion proteins to change conformation. It’s like a cult.
Potential Cause of iCJD
What is…
- Dura mater grafts
- Human pituitary-derived HGH
- Contaminated surgical instruments
Secondary illness that can occur in late CJD
Pneumonia
Proteins that are searched for when looking to test for CJD.
- 14-3-3
- Tau
Current precautions for suspected CJD samples.
None!
Name of one other illness that you would include in the differential diagnosis of CJD
Alzheimer’s
Huntington’s
Encephalitis
Stroke
The only current treatment for CJD
What is supportive care?
The reason for a person with CJD to fail a roadside sobriety test.
- Cerebellar ataxia
- unsteady gait
- unable to balance themselves
Full name of RT-QuIC
Real-time quaking-induced conversion
One entity to report a positive CJD specimen to.
- Chief Medical Officer of Health
- Medical Officer of Health of the zone
Genetic material requirement of a prion
Nothing!
How long does a typical sCJD case last?
What is weeks to a month