General Characteristics
Viral Replication
Diseases Caused by Picornaviruses
Diagnostics
Prevention and Treatment
100

Genetic material of Picarnoviridae Family 

 single-stranded positive-sense RNA viruses

100

Replication of picornaviruses occurs in this part of the cell.


 cytoplasm

100

This picornavirus causes the common cold.


 rhinovirus

100

Coxsackieviruses were first isolated in this U.S. town, which also lent the virus its name.


Coxsackie, New York

100

This inactivated vaccine is used against poliovirus.


 Salk vaccine

200

This virus in the Picornaviridae family causes poliomyelitis.


poliovirus

200

These cellular structures participate in assembling viral particles.


endoplasmic reticulum and membranes

200

Choose 1-3

sing a song

dance 

tell a joke

200

This method is used to detect viral antigens in samples.


ELISA (enzyme-linked immunosorbent assay)

200

This hygiene measure helps prevent the fecal-oral transmission of picornaviruses.


handwashing

300

Name three primary genera of picornaviruses that cause diseases in humans

 Enterovirus, Hepatovirus, and Rhinovirus

300

 This viral enzyme is essential for RNA synthesis from an RNA template.


RNA-dependent RNA polymerase

300

Enteroviruses often cause aseptic meningitis and this childhood illness known as “hand, foot, and mouth disease.”


enteroviral stomatitis

300

This diagnostic test detects the presence of viral RNA in cerebrospinal fluid, blood, or throat swabs, making it the gold standard for identifying Echovirus and Coxsackievirus infections.


PCR (polymerase chain reaction)

300

surprise 

500 points 

400

Push up 20 time 

You did it! Get your points 

400

 After initial replication, poliovirus spreads through the bloodstream to this part of the nervous system, where it causes motor neuron damage.



 spinal cord (especially the anterior horn)

400

Name the primary transmission route of picornaviruses like poliovirus.


ecal-oral route

400

ooopppss

minus 300p

400

Name the two main types of vaccines against poliovirus.


 oral polio vaccine (OPV) and inactivated polio vaccine (IPV)

500

This is the main structure of the picornavirus capsid that protects its genome.

icosahedral capsid

500

After entering the body, Echoviruses replicate in this lymphoid tissue before spreading to other organs.


Peyer’s patches in the small intestine

500

 This severe complication of poliomyelitis occurs due to motor neuron damage.


 paralysis

500

This type of cell culture is commonly used to grow and study picornaviruses.


What are HeLa cells

500

Coxsackievirus is divided into two groups:

Group A, associated with diseases like hand, foot, and mouth disease, and Group B, which can cause this severe complication affecting the heart myocarditis

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