Mood/Affect
Depression
Depressive Disorders
Pharmacology
Pharmacology continued
100
What is the difference between mood and affect?

mood: what the patient subjectively feel

affect: observable expression of mood 

100

What is depression?

sad or despondent mood or loss of interest in usual activities

100

What is MDD?

How long can it last?

s/sx?

-loss of interest in life and mild to severe depressed mood

-months or years

-anhedonia, insomnia, guilt, powerlessness, hopelessness

100

What is the action of SSRIs?

What are the meds?

-prevents serotonin from being reabsorbed as quickly, serotonin stays in the synapse longer to improve mood


-Celexa (citalopram), Lexapro (escitalopram), Luvox (fluvoxamine), Prozac (fluoxetine)

100

what is the action of tricyclics?

which patients should NOT use these drugs?

meds?

-blocks reabsorption of serotonin and norepinephrine, which causes these to build up so the brain will have more of this available to increase mood

-patients with cardiac problems

-Amitriptyline (elavil)

200

What is the continuum of mood and affect?

depression: low end

euthymia (no mood disturbances): middle

mania: extreme end

200

What is the period when someone is experiencing depression symptoms called?

depressive episode

200

What's the difference between MDD and a major depressive episode?

MDD will last for months or years 

major depressive episode: lasts less that 6 months 

200

What is the action of SNRIs?

What are some meds?

-blocks reabsorption of serotonin and noepinephrine 

-Cymbalta (duloxetine), Effexor (venlafaxine)

200

what is the action of MOAI's?

meds?

what foods should be avoided while taking these meds?

if patient eats food that should be avoided what may happen?

-blocks MOA (enzyme that breaks down neurotransmitters) so that neurotransmitters get a boost

-Nardil (phenelzine), Selegiline (zelepar)

-aged meats and chesses 

-hypertensive crisis

300

What are some words used to describe affect?

appropriate, inappropriate, elevated, depressed, blunted and flat


300
s/sx of depression?

lack of energy

agitation

abnormal eating patterns

feelings of hopelessness or despair

hallucinations, delusions, suicide

300

what is dysthmia?

Patients with dysthmia function well but will have problems with what?

-symptoms of depression everyday but sx are less severe than MDD

-relationships

300

-what is the action of NDRI's?

-what is the med?

-blocks the reuptake of norepinephrine and dopamine

-Wellbutrin (bupropion)

300

What are the two newer serotonin drugs that can be used?

why are these meds rarely prescribed?

-why do patients prefer these meds?


-Trintellix (vortioxitine), Viibryd (vilazodone)

-very expensive

-because these meds only fix the issue and doesn't leave them with other undesirable side effects

400

What are some things that can alter the mood?

maladaptive coping: denial, dependency

sleep disturbances: insomnia, too much sleep

somatization:physiological response to physchological stressors

difficulties adapting:day to day functioning

altered though processes: poor memory, hallucinations, impaired problem solving 

400

Risk factors of depression?

family hx of depression or other mental illnesses

female

hx of child abuse or trauma

poverty

inadequate support systems

inneffective mental health defense mechanisms

400

What is SAD?

Which hormone is increased with this d/o and which is decreased?

-symptoms of sadness and low energy in the winter months

- will have decreased serotonin and increased melatonin 

400

what is the action of SARI's?

meds?

-prevents reuptake of serotonin and block the function of serotonin transporter protein to increase amount of serotonin available in the brain 

-Nefazodone (serzone), Trazodone (desyrel)

400

-what are two natural supplements that patients taking antidepressants should avoid?

-ginkgo biloba and st. johns wart 

500

What are some verbal/ nonverbal cues we use for mood?


verbal: elated, happy, pleasure, frustrated, anger

nonverbal: smiling, frowning, blank look

500

Patho/Etiology

Patho: unknown

possible connection between depression and inflammation

Etiology: biological, environmental, genetic 

500

what is situational depression?

when do symptoms begin and how long will this last?

-change in mood or affect following a stressor

-symptoms begin about 3 months after the event has occured and can last for about 6 months 

500

what is the action of tetracyclics?

meds?

-stops neurotransmitters from binding to specific receptors and they build up in the synapse to increase mood

-Mirtazapine (remeron), Asamoxipine (asendin), Maprotiline (ludiomil)

500

Life span consideration for toddlers, preschoolers, school aged, older school aged, and adolescents (how will they act)?

-toddlers: regressive behaviors

-preschoolers: self destructive play themes

-school aged: grades plummett, loss of friends, increase or decrease in physical activity

-older school aged: running away, boredom

-adolescents: focus on violence, decreased self care, issues with parents and teachers

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