Name 4 of the symptoms for a major depressive episode from the DSM-5.
What is depressed mood, weight change, sleep disturbances, agitation/retardation, fatigue, guilt, decreased concentration, suicidal ideation, loss of interest or pleasure.
100
What is the mechanism behind the side effects of sedation and weight gain?
What is H1 receptor antagonism?
100
These 2 classes are considered first-line for the treatment of depression.
What are SSRIs and SNRIs?
100
This side effect is unique to both lithium and divalproex.
What is hand tremor?
100
The resolution of these symptoms should be seen within the first week of antidepressant therapy.
What are sleep and appetite?
200
Bipolar II is characterized by these mood states.
What are depression and hypomania?
200
These two antidepressants are not associated with withdrawal syndrome.
What are bupropion and mirtazapine?
200
This antidepressant would be good for someone experiencing comorbid insomnia.
What is mirtazapine?
200
This mood stabilizer has a narrow therapeutic index.
What is lithium carbonate?
200
This is the main goal of antidepressant therapy.
What is remission (resolution of depression symptoms)?
300
These are the target symptoms for the management of manic episodes.
What are mood, delusions, hallucinations and hyperactivity?
300
This is a side effect unique to SNRIs
What is hypertension?
300
These medications are considered first-line treatment for bipolar.
What are quetiapine (XR), lithium, or lamotrigine?
300
Lithium has these indications in bipolar therapy.
What are acute bipolar mania and bipolar maintenance monotherapy?
300
This is the length of time that is considered a sufficient therapeutic trial for an antidepressant.
What is 6 to 8 weeks?
400
Excluding MAOIs, this class of antidepressants should be avoided in patients at risk for intentional overdosing.
What is TCAs?
400
Use of this medication is contraindicated in patients with a history of seizures.
What is bupropion?
400
These are considered the "traditional" mood stabilizers.
What are lithium, carbamazepine, and valproic acid (divalproex)?
400
Thyroid monitoring is unique to this mood stabilizer.
What is lithium?
400
Monitoring platelets is unique to this bipolar medication.
What is divalproex/valproic acid?
500
These are the 3 side effects most associated with discontinuation of antidepressant therapy.
What is weight gain, insomnia, and sexual dysfunction?
500
QTc prolongation is a severe side effect unique to this class of antidepressants.
What is TCAs?
500
This is the only long-acting injectable SGA indicated for bipolar maintenance.
What is Risperdal Consta?
500
This mood stabilizer has indications for both mono and adjunct therapy for bipolar maintenance.
What is lamotrigine?
500
This is considered the target blood level for lithium carbonate.