time frame it takes for mutated cells to reach a malignant state.
What are decades
100
a disease of people who have lived long enough to experience the succession of events.
What is the increase in incidence with age
100
The tumor begins to develop when a cell experiences a mutation that makes the cell more likely to divide than it normally would.
What is Mutation
200
Done over a long period of time
have a 10 fold chance over people who don't do this.
What is smoking
200
Inhibits cell division
When mutated they inactivate these genes, which eliminates the critical inhibition of cell division that normally prevents excessive growth
What are Tumor Suppressor Genes
200
represents a breakdown of the processes that regulate the growth of normal cells and tissues.
What is cancer
200
increase the likelihood that harmful changes will occur
What are carcinogens
200
4
What is the number of stages of cancer
300
Over exposure to UV rays
Cells mutate and can cause cancer
What is sun exposure
300
the growth that normally ensures that each tissue and organ maintains the size and shape that the body needs.
What is what these two genes regulate
300
look and act differently from normal cells.
What are cancerous cells
300
the process of tumor formation will leapfrog over earlier steps and the malignant stat may take place in one for two decades.
What is inheriting a cancer
300
After the mutation occurs, the altered cell and its descendants grow and divide too often.
What is hyperplasia
400
Can be potent carcinogens and are used to keep bugs away.
What are pesticides
400
often damage these genes
What is cancer causing agents
400
three agents that can cause cancer
what is radiation, sun exposure, viruses, pesticides, cigarette smoke
400
helped to lead us to understanding the normal cell cycle.
What is cancer research
400
This cell and its descendants are very abnormal in both growth and appearance, if the tumor that has formed from these cells is still contained within its original tissue of origin.
What is in situ cancer (tumor)
500
not usually a cancer causing agent but some can act as causative factors.
What is a virus
500
what these genes control
What is the cell cycle
500
the name of this objective
What is the Development of cancer and Genetic damage and mutation
500
the estimated number of mutations needed for a cancer to become malignant
What is greater than 10
500
The cells descendants divide excessively and look abnormal.