First Trimester
Organ Development
Critical Periods
Fetal Milestones
Accessory Structures
100

This occurs when the blastocyst attaches to the uterine wall.

What is implantation?

100

This organ begins to form in week 3 and beats by week 5.

What is the heart?

100

The critical period for heart development is during these weeks.

What are weeks 3-8?

100

This reflex, essential for feeding, develops around week 28.

What is the sucking reflex?

100

This temporary organ forms from chorionic villi and provides respiration, nutrition, and excretion for the fetus.

What is the placenta?

200

By this week, the primitive heart begins to pump.

What is week 3?

200

These organs start developing in week 5 and produce urine by week 9.

What are the kidneys?

200

Neural tube defects can occur if this nutrient is deficient in early pregnancy.

What is folic acid?

200

The fetus begins to hear sounds outside the uterus around this week.

What is week 16?

200

 This fluid-filled sac surrounds and protects the developing fetus.

What is the amniotic sac?

300

This structure forms from the ectoderm and becomes the brain and spinal cord.

What is the neural tube?

300

This organ begins to form in week 3 and starts producing blood cells by week 6.

What is the liver?

300

Exposure to teratogens during this period can cause major structural abnormalities.

What is the embryonic period (weeks 3-8)?

300

Fetal movements, often called this, are typically felt around weeks 16-20.

What is quickening?

300

This structure connects the fetus to the placenta and contains two arteries and one vein.

What is the umbilical cord?

400

These three primary germ layers form during gastrulation.

What are the ectoderm, mesoderm, and endoderm?

400

These start to develop in week 4 and begin to move by week 9.

What are the limb buds?

400

This system is particularly vulnerable to alcohol exposure throughout pregnancy.

What is the central nervous system?

400

This protective substance begins to cover the fetus around week 20.

What is vernix caseosa?

400

This membrane forms the outer layer of the amniotic sac and contributes to placenta formation.

What is the chorion?

500

This membrane forms around the embryo and fills with amniotic fluid.

What is the amnion?

500

This organ starts forming in week 3 and has lobes by week 8.

What is the brain?

500

Cleft lip may occur if fusion of these processes is disrupted around week 6.

What are the maxillary and nasal processes?

500

Lung maturity is indicated by the production of this substance around week 35.

What is surfactant?

500

These maternal blood-filled spaces in the decidua basalis allow for nutrient and gas exchange.

What are the intervillous spaces (or lacunae)?

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