Advanced Techniques in Regenerative Medicine
This is the fabrication of complex tissue structures using layer-by-layer deposition of biomaterials and cells.
What is 3D bioprinting?
In tissue engineering, this term refers to the process of integrating engineered tissues with the host circulatory system to ensure adequate nutrient supply and waste removal.
What is vascularization?
This is a scaffold property that allows for gradual replacement by newly formed tissue.
What is biodegradation?
This complex cellular process involves the controlled death of cells within tissues, serving critical roles in tissue homeostasis, development, and regeneration in tissue engineering.
What is apoptosis?
It's the removal of cellular components from tissues to create acellular scaffolds for regeneration.
What is decellularization?
Researchers usually cite this as one of the biggest challenges in using tissue engineering for whole organ regeneration.
What are complex tissue architecture, vascularization, or innervation?
This is considered the "Tissue Engineeing Triad"?
What are cells, scaffolds, and signals (or growth factors)?
This term describes the directed movement of cells towards specific chemical signals or gradients, playing a pivotal role in processes such as tissue morphogenesis and wound healing.
What is chemotaxis or directed cell migration?
These are extracellular vesicles secreted by cells, used for cell communication and regenerative signaling.
What are exosomes?
This advanced technique in tissue engineering provides controlled environmental conditions, mechanical stimulation, and nutrient perfusion to engineered tissues, aiming to enhance tissue maturation and functionality.
What is bioreactor technology?
This technique is used to control the porosity (size and shape) of scaffolds in tissue engineering.
What is porogen leaching?
This term describes the process by which cells change their shape, polarity, and gene expression in response to mechanical forces, influencing tissue development and function in tissue engineering.
What is mechanotransduction or mechanical signaling in cells?
This technology involves the creation of miniature, three-dimensional organ-like structures from stem cells or tissue-specific progenitor cells, mimicking the structure and function of real organs.
What is organoid technology?
This tissue engineering technique allows you to create nanofibrous scaffolds with high surface area-to-volume ratio and tunable mechanical properties, suitable for various tissue regeneration applications.
What is electrospinning of nanofibrous scaffolds?
These are two methods to enhance the bioactivity of scaffolds in tissue engineering
What are surface modification, growth factor incorporation, and cell seeding?
This intricate cellular process involves the formation of specialized "these" that facilitate intercellular communication and tissue organization in tissue engineering.
Specialized cell-cell junctions, such as tight junctions and gap junctions,
This cutting-edge method involves the direct reprogramming of one cell type into another without passing through a pluripotent stage, offering new avenues for regenerative medicine and disease modeling.
What is direct cell reprogramming or transdifferentiation?
This advanced tissue engineering strategy utilizes biologically inspired scaffolds with dynamic mechanical properties that mimic the native tissue microenvironment, allowing for the modulation of cellular behavior and tissue development.
What is stimuli-responsive scaffold design or dynamic biomaterials?
If you're talking about the "Father" of Tissue Engineering. One of these names might show up.
Eugene Bell, Robert Langer, Y.C. Fung, Joseph Vacanti
This fundamental cellular process involves the degradation and crosslinking of the extracellular matrix (ECM) by specialized enzymes.
What is ECM remodeling?