Choose your Poison
This diuretic is the treatment of choice for lithium toxicity?
What is amiloride?
Draw the mechanism that explains why thiazide diuretics decrease calciuresis.
DRAW at the Board
This class of diuretics cause systemic vasodilatation.
What are loop diuretics?
This is the trial that included a cohort of IgA nephropathy patients in a study of SGLT-2 inhibitors as protein lowering agents.
What is the DAPA-CKD trial?
Name 3 WashU nephrologists that have twins.
Draw the mechanism by which patients can develop a "tolerance" to loop diuretics?
DRAW at the board!
This loop diuretic is the most ototoxic in its class.
What is ethacrynic acid?
This is the trial that demonstrated that SGLT-2 inhibitors may slow the progression of CKD in patients with eGFRs as low as 20.
What is the EMPA-Kidney trial?
This is where and what 3 fellowships Frank O'Brien completed.
What are Stanford nephrology, Royal College of Physicians (Dublin) nephrology and endocrinology?
This diuretic has been shown to have uricosuric properties and is the diuretic of choice in patients with severe gout.
What is bumetanide (bumex)?
Draw the mechanism of action by which loop and thiazide diuretics cause hypokalemia and metabolic alkalosis.
DRAW on the BOARD!
This diuretic causes this urine crystal.
What is triamterene?
This is the trial that showed that the addition of acetazolamide to loop diuretic therapy in patients with acute decompensated heart failure may result in a greater incidence of successful decongestion.
What is the ADVOR trial? (Acetazolamide in Decompensated Heart Failure with Volume Overload)
This nephrology faculty member plays the irish fiddle.
Who is Tim Yau?
This diuretic can be used to reduce the renal toxicity of antineoplastic platinum compounds.
What is mannitol?
Draw the portion of the tubule and transporters involved in the calciuretic effect of loop diuretics.
DRAW on the BOARD!
This class of diuretics has been shown to cause hyperglycemia.
What are thiazides?
This trial showed that patients who received chlorthalidone did not have a lower occurrence of major cardiovascular outcome events or non–cancer-related deaths than patients who received hydrochlorothiazide
What is the Diuretic Comparison Project?
This nephrology faculty member plays ice hockey.
This diuretic class is used to counteract respiratory alkalosis in high-altitude sickness.
Draw the mechanism(s) that show how at LEAST two different potassium sparing diuretics cause hyperkalemia.
DRAW at the board.
This class of diuretics may increase serum lithium concentrations.
What are thiazides?
This is the trial that showed that: among patients with acute decompensated heart failure, there were no significant differences in patients' global assessment of symptoms or in the change in renal function when diuretic therapy was administered by bolus as compared with continuous infusion or at a high dose as compared with a low dose.
What is the DOSE trial? (Diuretic Optimization Strategies Evaluation)
This nephrologist was a varsity javelin thrower in college?