DM

Brands/Generics

100

Farxiga

Dapagliflozin

200

Canagliflozin

Invokana

300

Glucophage

Metformin

400

Insulin Aspart

Novolog

500

Lantus

insulin Glargine

Values

100

normal 2hr PG

<11.1mmol/L or <200mg/L

200

criteria for the diagnosis using FBG

>7 mmol/L or >126mg/dL

300

normal A1C

<6.5%

400

pre-diabetes a1c value

5.7 - 6.4%

500

value for pre-diabetes using FBG

5.6 - 6.9 mmol/L

MOA

100

metformin

decrease hepatic glucose production

decrease intestinal absorption of glucose

improves insulin sensitivity by increasing peripheral glucose uptake

200

stimulate pancreatic beta cells

sulfonylurea

300

Alpha glucosidase inhibitor

inhibits hydrolysis of di-saccharides & complex carbs resulting in delayed glucose absorption

400

S/E of TZD

wgt gain, water retention, etc

Doses

100

max dose of Metformin

2550mg