History of DNA
DNA Structure
DNA Replication
DNA vs RNA
Miscellaneous
100
DNA-(TRANSCRIPTION)->pre mRNA (RNA processing)->mature mRNA-(TRANSLATION)->protein
Central Dogma of Biology
100
3 parts: phosphate, sugar, nitrogen base
What is a nucleotide
100
The location of DNA replication
What is the NUCLEUS
100
Name the type of RNA that: 1. makes up the ribosome 2. carries DNA message; leaves nucleus 3. transfers amino acid to ribosome
1. rRNA (ribosomal RNA) 2. mRNA (messenger RNA) 3. tRNA (transfer RNA)
100
The difference between Replication Fork- and Origin of Replication
Replication Fork= the base of separation of the 2 strands (moves in a 5' to 3' direction) Origin of Replication = Location that DNA Polymerase begins (will be different on lagging and leading strands)
200
mice and R and S strain; maybe transformation?
Griffith
200
Complementary base pairing means?
A-T G-C
200
The 1st step in replication is 1. _____________ caused by the enzyme 2. ______________.
1.Unwinding of 2 strands by breaking hydrogen bonds between bases 2.Enzyme: Helicase
200
Name 3 similarities of DNA and RNA
Both found in nucleus Both nucleic acids Both use nucleotides as building blocks.
200
Direction of replication is __________
5' to 3'
300
made 3D model of DNA structure
Watson & Crick
300
The different strands in the helix run in opposite directions
Antiparallel: One strand is 5' to 3'. The complementary strand is 3' to 5'.
300
small segments of replicated DNA formed on the lagging strand
What is Okazaki fragments
300
List 4 differences between DNA & RNA
1. DNA stays in nucleus; RNA nucleus & cytoplasm 2. DNA 2 strands; RNA 1 strand 3. DNA = deoxyribose sugar; RNA = ribose sugar 4. DNA = ATGC; RNA = AUGC
300
Glues Okazaki fragments together
Ligase
400
Created base pairing rule
Chargaff
400
Write the complementary DNA strand: A-T-G-C
T-A-C-G
400
One old strand and One new strand
What is the SEMI-CONSERVATIVE MODEL of DNA replication
400
Pyrimidines found in RNA
What are Uracil and Cysteine
400
x-ray diffraction images of DNA
Franklin & Wilkins
500
DNA/Protein mixtures of R and S strain (transforming principle exists)
Avery, McCleod, McCarty
500
Nitrogen bases are grouped into what 2 types of ringed structures?
What are purines (2 rings)- A & G What are pyrimidines (1 ring)- T & C
500
Adds DNA nucleotides
What is DNA Polymerase
500
Where in the cell do tRNA and rRNA do their jobs?
The Cytoplasm
500
Used bacteriophages; DNA is definately genetic material
Hershey & Chase
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