Enzymes & Proteins
The Process
The DNA Molecule
Mutations & Errors
Fun Facts
100

This enzyme unwinds the DNA double helix.


What is helicase?


100

DNA replication occurs during this phase of the cell cycle.


What is the S phase?


100

The building blocks of DNA are called 


What are nucleotides


100

A change in the DNA sequence is called a ______.


What is a mutation?


100


DNA replication happens in this part of the cell.


What is the nucleus?

200

This enzyme adds new nucleotides to the growing strand.


What is DNA polymerase?


200

The new DNA molecules each have one old and one new strand


What is semiconservative replication?


200

The sugar found in DNA is called


What is deoxyribose?

200


DNA polymerase can fix errors using this function.


What is proofreading

200


The human genome contains about this many base pairs.


What is 3 billion?

300


This enzyme connects Okazaki fragments.


What is DNA ligase?

300

Replication begins at specific points called


What are origins of replication?


300


Adenine pairs with this base.


What is thymine?

300


A mutation that doesn’t change the amino acid sequence.


What is a silent mutation

300


The scientist(s) who proposed the double helix model of DNA.


Who are Watson and Crick?

400

This enzyme adds short RNA primers to start replication.


What is primase?


400

The strand synthesized continuously toward the replication fork.


What is the leading strand?


400


DNA strands are oriented in opposite directions this term describes that.

What is antiparallel?

What is antiparallel?

400


When an incorrect base is added during replication.


What is a base substitution?

400


The enzyme that helps prevent chromosome shortening at the ends.


What is telomerase?

500

This protein prevents the strands from rejoining after unwinding.


What are single-strand binding proteins (SSBs


500

The strand made in short segments away from the fork.


What is the lagging strand?


500


The strong bonds between sugar and phosphate groups are called ______ bonds.


What are phosphodiester bonds?

500


Radiation and chemicals that cause mutations are called ______.


What are mutagens?

500


This type of replication occurs in circular DNA, like in bacteria.


What is the theta model or rolling circle replication?

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