Location
This is the site where helicase splits the DNA
Replication fork
He is known for his work with the modes of heredity in pea plants.
Mendel
This is the enzyme that “unzips” the gene
Helicase
What does DNA stand for?
Deoxyribose nucleic acid
Replication Fork, helical unzips the double stranded DNA into two strands
What is the first step of DNA replication?
Where DNA replication takes place in a eukaryotic and a prokaryotic cell
Eukaryotic- Nucleus , Prokaryotic- cytoplasm
These two scientists said that DNA strands are complementary to one another.
Watson and Crick
This is the enzyme that links all the bases on the lagging strand. This is necessary in joining the strands of DNA together
DNA Ligase
Monomers of nucleic acid.
Adenine, thymine, guanine, cytosine.
What are nucleotides?
RNA primer (generated from DNA primase) binds to the 3’ end of the leading strand
What is the second step of DNA replication
The nickname for the location of the beginning of replication
Bubbles
Stated that genes were located on chromosomes.
Morgan
This enzyme doubles the amount of DNA in a cell during cell division. This enzyme is responsible for:
- Catalyzing the formation of new DNA strands.
- Adding nucleotides to the existing DNA strand.
- Repairing damaged DNA strands.
DNA Polymerase
Initiation: proteins bind to the origin of replication while helicase unwinds the DNA helix and two replication forks are formed at the origin of replication. Elongation: a primer sequence is added with complementary RNA nucleotides, which are then replaced by DNA nucleotides.
Termination: primers are removed and replaced with new DNA nucleotides and the backbone is sealed by DNA ligase.
What are the three main stages of DNA replication?
DNA polymerase creates the new strand through elongation.
What is the third step of DNA replication?
When one synthesized strand pairs with one parent strand
Semiconservative model
These two men tried to determine whether protein or DNA was the basis of hereditary material.
Hershey and Chase
This tells the DNA polymerase to begin adding new bases to the template LAGGING strand
RNA primase
During elongation the leading strand is made continuously, while the lagging strand is made in pieces.
Okazaki fragments
Lagging strand begins replication by binding with multiple primers. DNA polymerase then adds pieces of DNA, called Okazaki fragments, to the strand between primers
What is the fourth step of DNA replication?
Where RNA (primer) is inserted in the sequence
Point of initiation
This scientist "accidentally" discovered DNA while studying the composition of white blood cells
Friedrich Miescher
joins individual nucleotides to produce a new strand of DNA then proofreads it.
DNA polymerase l
The strand that opens in the 3' to 5' direction towards the replication fork and has discontinuous replication is referred to as
Lagging Strand
Termination
What is the final step of DNA replication?