Anticoagulant Mechanisms
This anticoagulant enhances antithrombin activity to inhibit thrombin and factor Xa.
What is heparin
This anticoagulant increases risk of epidural hematoma with neuraxial catheters.
What is LMWH
This diuretic inhibits carbonic anhydrase in the proximal tubule.
What is acetazolamide
These drugs inhibit HMG-CoA reductase.
What are statins
A trauma patient with hemorrhage receives TXA to stabilize this structure.
What is a fibrin clot
LMWH primarily inhibits this clotting factor.
What is factor Xa
This renal condition makes LMWH unsafe due to prolonged effect.
What is renal failure
Loop diuretics block this transporter in the thick ascending limb.
What is Na-K-2Cl cotransporter
Statins primarily reduce this lipoprotein.
What is LDL
A cardiac bypass patient requires this monitoring test for high-dose heparin.
What is ACT
This direct thrombin inhibitor is preferred in renal failure due to hepatic clearance.
What is argatroban
This anticoagulant reversal agent does NOT fully reverse LMWH.
What is protamine
This loop diuretic is nonsulfonamide and useful for sulfa allergy.
What is ethacrynic acid
This lipid particle carries cholesterol from liver to tissues.
What is LDL
A patient with HIT requires this class of anticoagulants.
What are direct thrombin inhibitors
This anticoagulant inhibits vitamin K–dependent clotting factor synthesis.
What is warfarin
Surgery should typically occur this many days after stopping warfarin.
What is 5 days
Loop diuretics commonly cause this electrolyte abnormality.
What is hypokalemia
This lipid particle is responsible for reverse cholesterol transport.
What is HDL
This drug is preferred anticoagulant in HIT with renal failure.
What is argatroban
These clotting factors are inhibited by warfarin.
What are factors II, VII, IX, and X
This complication can occur with heparin due to antibodies to platelet factor IV.
What is heparin-induced thrombocytopenia (HIT)
These diuretics act on the distal tubule blocking the Na-Cl transporter.
What are thiazide diuretics
These biologics lower LDL by inhibiting PCSK9.
What are PCSK9 inhibitors
A diabetic patient receiving NPH insulin has increased risk of reaction to this reversal drug.
What is protamine