Basics
differences between direct and indirect caloimetry
Direct = heat production in proportion to metabolic rate
Indirect = Relationship between O2 consumption and amount of heat produced by the body
Rate limiting enzyme name for PCr
Creatine kinase
Name of rate limiting enzyme
Phosphofructosekinase
Krebs depends on the availability of what
Acetyl-CoA
What is the rate limiting enzyme of the ETC
Cytochrome oxidase
Compare exergonic from endergonic reactions
exergonic = creates energy
endergonic = requires energy
Example of an activity that relies on the PCr system
40 yd dash
Where does glycolysis occur
Cytoplasm
Where does the Keb cycle (CAC) and ETC occur
Mitochondria
What is the rate limiting enzyme of the Kreb cycle
Isocitrate dehydrogenase
What is a kcal
The amount of energy it takes to raise 1L of water and 1degree Celsius
How long can you use the PCr system
up to 15secs
What are the products of glycolysis for one molecule of glucose
2ATP, 2NADP, 2 pyruvate
1 NADH is how much ATP
2.5 ATP per NADH
What enzyme is involved in glyconeogenesis and what dies it do
Phosphorylase breaks down glycogen into glucose
What are the 2 laws of thermodynamics
1st law: energy cannot be created or destroyed but can change its form
2nd law: energy transfer will always proceed in the direction of increased entropy
What is the rate-limiting enzyme stimulators and inhibitors
stimulators = ADP
inhibitors = ATP
What substrate does pyruvate kinase convert into pyruvate
phosphoenlopyruvate
What substances can be utilized aerobically but NOT anaerobically
Fats and proteins
What is hormone sensitive lipase
enzyme that breaks down triglycerides and stimulated by growth hormone and epinephrine
What function do carbohydrates perform
to catabolize into quick fast ATP production going where its needed; brain, muscles, vital organs
What is the creatine intake recommendation
15-25 g/day for 5-7 days
What stimulates and inhibits the rate of limiters of glycolysis
Stimulators = ADP, AMP, Pi, increased pH
Inhibitors = ATP, CP, Citrate, decreased pH
What stimulates and inhibits the rate of enzymatic activity in the ETC
stimulates = ADP and Pi
inhibits = ATP
What do all 4 rate limiting enzymes have for stimulation and inhibition
ADP and ATP