Endocrinology and Metabolism
Enzyme deficiency characterized by virilization, hypotension, hyperkalemia, and cortisol deficiency
21-hydroxylase deficiency
Hematologic malignancy associated with translocation of chromosomes 15 and 17
Acute promyelocytic leukemia
Woman whose work set the standards for modern nursing and earned the nickname "the Lady with the Lamp"
Florence Nightingale
Condition suggested by ankle-brachial index less than 0.9 in a patient with calf pain on exertion
Peripheral artery disease (PAD), accept arterial obstruction/occlusion
Non-contraceptive treatment for PMS and premenstrual dysphoria
Selective serotonin reuptake inhibitors (SSRIs)
Autoimmune skin condition associated with autoimmune adrenalitis
Vitiligo
Disease caused by beta-globin mutation leading to vaso-occlusion
Sickle cell disease
A paper prototype of this medical instrument was described by Dr. Laënnec in 1834
Stethoscope
Cardiac syndrome with short PR interval, delta wave, and widened QRS complex
Wolff-Parkinson-White (WPW) syndrome
Breast mass imaging modality for women younger than 30 years of age or who are pregnant
Ultrasonography
Imaging study to detect extent and location of Paget disease of bone
Bone scintigraphy (accept radionuclide bone scan)
The study of heritable alterations in gene expression that occur outside of the DNA sequence
Epigenetics
First Native American woman to become a physician
Dr. Susan La Flesche Picotte
Autosomal dominant genetic disorder associated with a defect in myocardial sodium channels, abnormal EKG findings, and sudden cardiac death
Brugada syndrome
This criteria, established in 2003, are used to diagnose polycystic ovarian syndrome
Rotterdam criteria
Syndrome defined by medullary thyroid cancer, pheochromocytoma, and primary hyperparathyroidism
Multiple endocrine neoplasia type 2A (MEN2A)
Ability of a mutation in a single gene to produce more than 1 phenotypic effect
Pleiotropy
This French neurologist, who was replaced by Lou Gehrig in an eponymous condition, was a pioneer in localizing neurologic lesions
Jean-Martin Charcot
Pathognomic finding of concentric ventricular wall thickness with low QRS voltage
Amyloidosis
Most appropriate blood test for a woman with headache, oligomenorrhea and galactorrhea
Prolactin level
Required cancer screening in individuals with growth hormone excess
Colonoscopy (accept colon cancer screening)
Term for alteration of chromosome gene expression without changing the nucleotide base sequence
Epigenetic change
The first successful human heart transplant was performed in this year
1967
Anti-anginal medication associated with reduced intracellular calcium levels and QT-prolongation
Ranolazine
Syndrome caused due to germline mutation in one of the DNA mismatch repair genes (MLH1, MSH2, MSH6, PMS2)
Lynch syndrome