Database that contains information on drugs and other chemicals to which breastfeeding mothers may be exposed
What is LactMed?
The probability that a positive results measured by an instrument represents an actual and true positive case
What is positive predictive value (PPV)?
Minimum set of items for reporting systematic reviews and meta-analyses
What is PRISMA?
A dose of ondansetron in the last 24 hours
What is one of the exclusion criteria for automatic IV to PO conversion?
Performance improvement tool that is a focused effort to evaluate medication use processes or medication treatment response with the goal of optimal patient outcomes
What is a medication use evaluation (MUE)?
Provides information on diagnosis, cause, frequency, clinical patterns, and management of livery injury attributable to prescription and nonprescription medications (and herbal and dietary supplements)
What is LiverTox?
The probability that a disease-free individual will have a negative result and it is a true negative rate of the screening test
What is specificity?
Quantitative, statistical synthesis that yields a single best estimate of the treatment effect
What is a meta-analysis?
Giving a dose of vancomycin then waiting for about 24 hours, drawing a level, and re-dosing if the level is < 15 mcg/mL
What is pulse or PRN vancomycin dosing?
Measure of association that quantifies ratio of incidence
What is relative risk?
Database provided by the National Library of Medicine and NIH containing information on prescription and non-prescription drugs (human and animal), medical devices, and gases
What is DailyMed?
Describes the strength of an association between two variables, denoted by a single statistic
What is correlation?
Refers to how much results of each individual trial are compatible with results of any other trials included in a meta-analysis
What is homogeneity?
20 mcg/mL
What is the increase in vancomycin level after a 15 mg/kg dose?
Outcomes that illuminate the etiology, prevalence, and pathophysiology of diseases
What is disease-oriented evidence (DOE)?
Strength and quality of evidence, patient preference, cost-effectiveness, convenience, side effects
What are considerations for using guidelines in clinical practice?
Describes the average value of y (response) as a function of changing x (predictor) and helps identify how variables affect each other
What is regression?
Graphical display of estimated results from a number of scientific studies addressing the same question, including overall results
What is a forest plot?
The peak level reached when giving a loading dose of 20 mg/kg to a 100 kg patient
What is 26.6 mcg/mL? (26-27)
Measure of association between exposure and an outcome for retrospective studies
What is odds ratio?
Observed early vasopressin demonstrated catecholamine-sparing effect in septic shock but was not associated with difference in mortality
What is the VANISH trial?
Tells you have much change in your dependent variable can be predicted by a change in your independent variable
What is r2 (coefficient of determination)?
Likelihood of a study being published based on the findings of the study
What is publication bias?
A reason to change a person from vancomycin to nafcillin
What is a culture result of MSSA?
Describes the extent to which a cause and effect relationship established in a study cannot be explained by other factors
What is internal validity?