400
4. Select all that apply concerning the drug….Aspirin
A. Causes reversible inhibition of cyclooxygenase
B. Provides relief of mild to moderate pain
C. Reduces fever
D. Is anti-inflammatory
E. Remains a drug often used to treat osteoarthritis and rheumatoid arthritis
F. Can cause serious toxicity
What is B, C, D, E, and F……Causes irreversible inhibition of cyclooxygenase. Cells need to make new receptors to replace those bound by aspirin. Platelets lack the ability to regenerate their receptors, so aspirin inhibits the platelets aggregation ability for the remainder of the platelets life (about 8 days)